Detection and characterization of Leishmania in tissues of patients with post kala-azar dermal leishmaniasis using a specific monoclonal antibody

A Ismail; A Kharazmi; H Permin; A M el Hassan

Detection and characterization of Leishmania in tissues of patients with post kala-azar dermal leishmaniasis using a specific monoclonal antibody

A Ismail, A Kharazmi, H Permin, A M el Hassan

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

29 Citationer (Scopus)

Abstract

Udgivelsesdato: null-null

Originalsprog	Engelsk
Tidsskrift	Transactions of the Royal Society of Tropical Medicine and Hygiene
Vol/bind	91
Udgave nummer	3
Sider (fra-til)	283-5
Antal sider	2
ISSN	0035-9203
Status	Udgivet - 1997

Bibliografisk note

Keywords: Animals; Antibodies, Monoclonal; Antibody Specificity; Antigens, Protozoan; Humans; Immunoenzyme Techniques; Leishmania donovani; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Lymph Nodes; Skin

Citationsformater

Detection and characterization of Leishmania in tissues of patients with post kala-azar dermal leishmaniasis using a specific monoclonal antibody. / Ismail, A; Kharazmi, A; Permin, H; el Hassan, A M.

I: Transactions of the Royal Society of Tropical Medicine and Hygiene, Bind 91, Nr. 3, 1997, s. 283-5.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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title = "Detection and characterization of Leishmania in tissues of patients with post kala-azar dermal leishmaniasis using a specific monoclonal antibody",

abstract = "Sections from skin lesions and draining lymph nodes of patients with post kala-azar dermal leishmaniasis were examined using an immunoperoxidase method and a monoclonal antibody directed against Leishmania donovani. Parasites were detected in 22 of 25 biopsies (88%). In parallel sections stained by haematoxylin and eosin, parasites were detected in only 5 of 25 of the biopsies (20%). The demonstration of whole parasites or parasite antigen is diagnostic.",

author = "A Ismail and A Kharazmi and H Permin and {el Hassan}, {A M}",

note = "Keywords: Animals; Antibodies, Monoclonal; Antibody Specificity; Antigens, Protozoan; Humans; Immunoenzyme Techniques; Leishmania donovani; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Lymph Nodes; Skin",

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T1 - Detection and characterization of Leishmania in tissues of patients with post kala-azar dermal leishmaniasis using a specific monoclonal antibody

AU - Ismail, A

AU - Kharazmi, A

AU - Permin, H

AU - el Hassan, A M

N1 - Keywords: Animals; Antibodies, Monoclonal; Antibody Specificity; Antigens, Protozoan; Humans; Immunoenzyme Techniques; Leishmania donovani; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Lymph Nodes; Skin

PY - 1997

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N2 - Sections from skin lesions and draining lymph nodes of patients with post kala-azar dermal leishmaniasis were examined using an immunoperoxidase method and a monoclonal antibody directed against Leishmania donovani. Parasites were detected in 22 of 25 biopsies (88%). In parallel sections stained by haematoxylin and eosin, parasites were detected in only 5 of 25 of the biopsies (20%). The demonstration of whole parasites or parasite antigen is diagnostic.

AB - Sections from skin lesions and draining lymph nodes of patients with post kala-azar dermal leishmaniasis were examined using an immunoperoxidase method and a monoclonal antibody directed against Leishmania donovani. Parasites were detected in 22 of 25 biopsies (88%). In parallel sections stained by haematoxylin and eosin, parasites were detected in only 5 of 25 of the biopsies (20%). The demonstration of whole parasites or parasite antigen is diagnostic.

M3 - Journal article

C2 - 9231195

VL - 91

SP - 283

EP - 285

JO - Transactions of the Royal Society of Tropical Medicine and Hygiene

JF - Transactions of the Royal Society of Tropical Medicine and Hygiene

SN - 0035-9203

IS - 3

ER -