Detection and interpretation of 8-oxodG and 8-oxoGua in urine, plasma and cerebrospinal fluid

Henrik E Poulsen; Laia Llovera Nadal; Kasper Broedbaek; Peter E Nielsen; Allan Weimann

doi:10.1016/j.bbagen.2013.06.009

Detection and interpretation of 8-oxodG and 8-oxoGua in urine, plasma and cerebrospinal fluid

Henrik E Poulsen, Laia Llovera Nadal, Kasper Broedbaek, Peter E Nielsen, Allan Weimann

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

138 Citationer (Scopus)

Abstract

DNA and RNA oxidations have been linked to diseases such as cancer, arteriosclerosis, neurodegeneration and diabetes. The prototype base modification studied is the 8-hydroxylation of guanine. DNA integrity is maintained by elaborate repair systems and RNA integrity is less studied but relies mainly on degradation.

Originalsprog	Engelsk
Tidsskrift	BBA General Subjects
Vol/bind	1840
Udgave nummer	2
Sider (fra-til)	801-808
Antal sider	8
ISSN	0304-4165
DOI	https://doi.org/10.1016/j.bbagen.2013.06.009
Status	Udgivet - feb. 2014

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10.1016/j.bbagen.2013.06.009

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Citationsformater

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title = "Detection and interpretation of 8-oxodG and 8-oxoGua in urine, plasma and cerebrospinal fluid",

abstract = "DNA and RNA oxidations have been linked to diseases such as cancer, arteriosclerosis, neurodegeneration and diabetes. The prototype base modification studied is the 8-hydroxylation of guanine. DNA integrity is maintained by elaborate repair systems and RNA integrity is less studied but relies mainly on degradation.",

author = "Poulsen, {Henrik E} and Nadal, {Laia Llovera} and Kasper Broedbaek and Nielsen, {Peter E} and Allan Weimann",

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T1 - Detection and interpretation of 8-oxodG and 8-oxoGua in urine, plasma and cerebrospinal fluid

AU - Poulsen, Henrik E

AU - Nadal, Laia Llovera

AU - Broedbaek, Kasper

AU - Nielsen, Peter E

AU - Weimann, Allan

PY - 2014/2

Y1 - 2014/2

N2 - DNA and RNA oxidations have been linked to diseases such as cancer, arteriosclerosis, neurodegeneration and diabetes. The prototype base modification studied is the 8-hydroxylation of guanine. DNA integrity is maintained by elaborate repair systems and RNA integrity is less studied but relies mainly on degradation.

AB - DNA and RNA oxidations have been linked to diseases such as cancer, arteriosclerosis, neurodegeneration and diabetes. The prototype base modification studied is the 8-hydroxylation of guanine. DNA integrity is maintained by elaborate repair systems and RNA integrity is less studied but relies mainly on degradation.

U2 - 10.1016/j.bbagen.2013.06.009

DO - 10.1016/j.bbagen.2013.06.009

M3 - Journal article

C2 - 23791936

SN - 0304-4165

VL - 1840

SP - 801

EP - 808

JO - BBA General Subjects

JF - BBA General Subjects

IS - 2

ER -