Dietary factors impact on the association between CTSS variants and obesity related traits

Henri Hooton; Lars Henrik Ängquist; Claus Holst; Jorg Hager; Francis Rousseau; Rikke D Hansen; Anne Tjønneland; Nina Roswall; Daphne L van der A; Kim Overvad; Marianne Uhre Jakobsen; Heiner Boeing; Karina Meidtner; Domenico Palli; Giovanna Masala; Nabila Bouatia-Naji; Wim H M Saris; Edith J M Feskens; Nicolas J Wareham; Karani S Vimaleswaran; Dominique Langin; Ruth J F Loos; Thorkild I A Sørensen; Karine Clément

doi:10.1371/journal.pone.0040394

Dietary factors impact on the association between CTSS variants and obesity related traits

Henri Hooton, Lars Henrik Ängquist, Claus Holst, Jorg Hager, Francis Rousseau, Rikke D Hansen, Anne Tjønneland, Nina Roswall, Daphne L van der A, Kim Overvad, Marianne Uhre Jakobsen, Heiner Boeing, Karina Meidtner, Domenico Palli, Giovanna Masala, Nabila Bouatia-Naji, Wim H M Saris, Edith J M Feskens, Nicolas J Wareham, Karani S VimaleswaranDominique Langin, Ruth J F Loos, Thorkild I A Sørensen, Karine Clément

Institut for Folkesundhedsvidenskab

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

12 Citationer (Scopus)

Abstract

Cathepsin S, a protein coded by the CTSS gene, is implicated in adipose tissue biology--this protein enhances adipose tissue development. Our hypothesis is that common variants in CTSS play a role in body weight regulation and in the development of obesity and that these effects are influenced by dietary factors--increased by high protein, glycemic index and energy diets.

Originalsprog	Engelsk
Tidsskrift	P L o S One
Vol/bind	7
Udgave nummer	7
Sider (fra-til)	e40394
ISSN	1932-6203
DOI	https://doi.org/10.1371/journal.pone.0040394
Status	Udgivet - 2012

Adgang til dokumentet

10.1371/journal.pone.0040394

Citationsformater

Hooton, H., Ängquist, L. H., Holst, C., Hager, J., Rousseau, F., Hansen, R. D., Tjønneland, A., Roswall, N., van der A, D. L., Overvad, K., Jakobsen, M. U., Boeing, H., Meidtner, K., Palli, D., Masala, G., Bouatia-Naji, N., Saris, W. H. M., Feskens, E. J. M., Wareham, N. J., ... Clément, K. (2012). Dietary factors impact on the association between CTSS variants and obesity related traits. P L o S One, 7(7), e40394. https://doi.org/10.1371/journal.pone.0040394

Hooton, H, Ängquist, LH, Holst, C, Hager, J, Rousseau, F, Hansen, RD, Tjønneland, A, Roswall, N, van der A, DL, Overvad, K, Jakobsen, MU, Boeing, H, Meidtner, K, Palli, D, Masala, G, Bouatia-Naji, N, Saris, WHM, Feskens, EJM, Wareham, NJ, Vimaleswaran, KS, Langin, D, Loos, RJF, Sørensen, TIA & Clément, K 2012, 'Dietary factors impact on the association between CTSS variants and obesity related traits', P L o S One, bind 7, nr. 7, s. e40394. https://doi.org/10.1371/journal.pone.0040394

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title = "Dietary factors impact on the association between CTSS variants and obesity related traits",

abstract = "Cathepsin S, a protein coded by the CTSS gene, is implicated in adipose tissue biology--this protein enhances adipose tissue development. Our hypothesis is that common variants in CTSS play a role in body weight regulation and in the development of obesity and that these effects are influenced by dietary factors--increased by high protein, glycemic index and energy diets.",

author = "Henri Hooton and {\"A}ngquist, {Lars Henrik} and Claus Holst and Jorg Hager and Francis Rousseau and Hansen, {Rikke D} and Anne Tj{\o}nneland and Nina Roswall and {van der A}, {Daphne L} and Kim Overvad and Jakobsen, {Marianne Uhre} and Heiner Boeing and Karina Meidtner and Domenico Palli and Giovanna Masala and Nabila Bouatia-Naji and Saris, {Wim H M} and Feskens, {Edith J M} and Wareham, {Nicolas J} and Vimaleswaran, {Karani S} and Dominique Langin and Loos, {Ruth J F} and S{\o}rensen, {Thorkild I A} and Karine Cl{\'e}ment",

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T1 - Dietary factors impact on the association between CTSS variants and obesity related traits

AU - Hooton, Henri

AU - Ängquist, Lars Henrik

AU - Holst, Claus

AU - Hager, Jorg

AU - Rousseau, Francis

AU - Hansen, Rikke D

AU - Tjønneland, Anne

AU - Roswall, Nina

AU - van der A, Daphne L

AU - Overvad, Kim

AU - Jakobsen, Marianne Uhre

AU - Boeing, Heiner

AU - Meidtner, Karina

AU - Palli, Domenico

AU - Masala, Giovanna

AU - Bouatia-Naji, Nabila

AU - Saris, Wim H M

AU - Feskens, Edith J M

AU - Wareham, Nicolas J

AU - Vimaleswaran, Karani S

AU - Langin, Dominique

AU - Loos, Ruth J F

AU - Sørensen, Thorkild I A

AU - Clément, Karine

PY - 2012

Y1 - 2012

N2 - Cathepsin S, a protein coded by the CTSS gene, is implicated in adipose tissue biology--this protein enhances adipose tissue development. Our hypothesis is that common variants in CTSS play a role in body weight regulation and in the development of obesity and that these effects are influenced by dietary factors--increased by high protein, glycemic index and energy diets.

AB - Cathepsin S, a protein coded by the CTSS gene, is implicated in adipose tissue biology--this protein enhances adipose tissue development. Our hypothesis is that common variants in CTSS play a role in body weight regulation and in the development of obesity and that these effects are influenced by dietary factors--increased by high protein, glycemic index and energy diets.

U2 - 10.1371/journal.pone.0040394

DO - 10.1371/journal.pone.0040394

M3 - Journal article

SN - 1932-6203

VL - 7

SP - e40394

JO - P L o S One

JF - P L o S One

IS - 7

ER -