Direct N9-arylation of purines with aryl halides

Anders Foller Larsen, Trond Ulven

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23 Citationer (Scopus)
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Abstract

An efficient method for N-arylation of purines is reported. The N-arylation is catalysed by Cu(i) and 4,7-bis(2-hydroxyethylamino)-1,10-phenanthroline (BHPhen) in aqueous DMF or ethanol. The reaction generally proceeds with high selectivity for the N(9)-position.
OriginalsprogEngelsk
TidsskriftChemical Communications
Vol/bind50
Udgave nummer39
Sider (fra-til)4997-4999
Antal sider3
ISSN1359-7345
DOI
StatusUdgivet - 21 maj 2014
Udgivet eksterntJa

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