Direct N9-arylation of purines with aryl halides

Anders Foller Larsen; Trond Ulven

doi:10.1039/c3cc48642g

Direct N9-arylation of purines with aryl halides

Anders Foller Larsen
, Trond Ulven

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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Abstract

An efficient method for N-arylation of purines is reported. The N-arylation is catalysed by Cu(i) and 4,7-bis(2-hydroxyethylamino)-1,10-phenanthroline (BHPhen) in aqueous DMF or ethanol. The reaction generally proceeds with high selectivity for the N(9)-position.

Originalsprog	Engelsk
Tidsskrift	Chemical Communications
Vol/bind	50
Udgave nummer	39
Sider (fra-til)	4997-4999
Antal sider	3
ISSN	1359-7345
DOI	https://doi.org/10.1039/c3cc48642g
Status	Udgivet - 21 maj 2014
Udgivet eksternt	Ja

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10.1039/c3cc48642gLicens: CC BY

c3cc48642gLicens: CC BY

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Citationsformater

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title = "Direct N9-arylation of purines with aryl halides",

abstract = "An efficient method for N-arylation of purines is reported. The N-arylation is catalysed by Cu(i) and 4,7-bis(2-hydroxyethylamino)-1,10-phenanthroline (BHPhen) in aqueous DMF or ethanol. The reaction generally proceeds with high selectivity for the N(9)-position.",

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T1 - Direct N9-arylation of purines with aryl halides

AU - Larsen, Anders Foller

AU - Ulven, Trond

PY - 2014/5/21

Y1 - 2014/5/21

N2 - An efficient method for N-arylation of purines is reported. The N-arylation is catalysed by Cu(i) and 4,7-bis(2-hydroxyethylamino)-1,10-phenanthroline (BHPhen) in aqueous DMF or ethanol. The reaction generally proceeds with high selectivity for the N(9)-position.

AB - An efficient method for N-arylation of purines is reported. The N-arylation is catalysed by Cu(i) and 4,7-bis(2-hydroxyethylamino)-1,10-phenanthroline (BHPhen) in aqueous DMF or ethanol. The reaction generally proceeds with high selectivity for the N(9)-position.

U2 - 10.1039/c3cc48642g

DO - 10.1039/c3cc48642g

M3 - Journal article

SN - 1359-7345

VL - 50

SP - 4997

EP - 4999

JO - Chemical Communications

JF - Chemical Communications

IS - 39

ER -