Directed evolution of cytochrome P450 enzymes for biocatalysis: exploiting the catalytic versatility of enzymes with relaxed substrate specificity

James B. Y. H. Behrendorff; Weiliang Huang; Elizabeth M. J. Gillam

doi:10.1042/BJ20141493

Directed evolution of cytochrome P450 enzymes for biocatalysis: exploiting the catalytic versatility of enzymes with relaxed substrate specificity

James B. Y. H. Behrendorff, Weiliang Huang, Elizabeth M. J. Gillam

Publikation: Bidrag til tidsskrift › Review › peer review

69 Citationer (Scopus)

Originalsprog	Engelsk
Tidsskrift	Biochemical Journal
Vol/bind	467
Sider (fra-til)	1-15
ISSN	0264-6021
DOI	https://doi.org/10.1042/BJ20141493
Status	Udgivet - 2015
Udgivet eksternt	Ja

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@article{34010ab5d86246d5a73120163805e812,

title = "Directed evolution of cytochrome P450 enzymes for biocatalysis: exploiting the catalytic versatility of enzymes with relaxed substrate specificity",

keywords = "biocatalysis, cytochrome P450, directed evolution, DNA shuffling, drug discovery, substrate ambiguity",

author = "Behrendorff, {James B. Y. H.} and Weiliang Huang and Gillam, {Elizabeth M. J.}",

year = "2015",

doi = "10.1042/BJ20141493",

language = "English",

volume = "467",

pages = "1--15",

journal = "Biochemical Journal",

issn = "0264-6021",

publisher = "Portland Press Ltd.",

}

TY - JOUR

T1 - Directed evolution of cytochrome P450 enzymes for biocatalysis: exploiting the catalytic versatility of enzymes with relaxed substrate specificity

AU - Behrendorff, James B. Y. H.

AU - Huang, Weiliang

AU - Gillam, Elizabeth M. J.

PY - 2015

Y1 - 2015

KW - biocatalysis

KW - cytochrome P450

KW - directed evolution

KW - DNA shuffling

KW - drug discovery

KW - substrate ambiguity

U2 - 10.1042/BJ20141493

DO - 10.1042/BJ20141493

M3 - Review

SN - 0264-6021

VL - 467

SP - 1

EP - 15

JO - Biochemical Journal

JF - Biochemical Journal

ER -