Abstract
Wang et al1 evaluated discordances in the estimated glomerular filtration rate (eGFR) based on creatinine (eGFRcr), cystatin C (eGFRcys), or their combination (eGFRcr-cys). They used data from the 2021 CKD-EPI external validation cohort, which included 4,050 ambulatory participants (mean age of 57.0 years and mean measured GFR [mGFR] of 76.4 mL/min/1.73m2).2 Defining eGFRdiff as a discordance between eGFRcys and eGFRcr larger than ±15 mL/min/1.73m2, the authors found that 21% of patients had a negative discordance (eGFRcr higher) and 10% had a positive discordance (eGFRcys higher). In both groups, eGFRcr-cys yielded the best performance relative to mGFR, according to bias and P30. The authors acknowledge that their study was limited by the lack of multimorbid or hospitalized patients.
Originalsprog | Engelsk |
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Artikelnummer | 100743 |
Tidsskrift | Kidney Medicine |
Vol/bind | 5 |
Udgave nummer | 12 |
Antal sider | 2 |
ISSN | 2590-0595 |
DOI | |
Status | Udgivet - 2023 |
Bibliografisk note
Funding Information:The authors declare that they have no relevant financial interests. Received September 4, 2023. Accepted September 10, 2023 after editorial review by the Editor-in Chief.