Abstract
INTRODUCTION: In patients with myasthenia gravis (MG), muscle strength is expected to decrease gradually during the day due to physical activities.
METHODS: Isometric muscle strength at the shoulder, knee, and ankle was determined in 10 MG patients (MGFA class II-IV) who were receiving usual medical treatment and in 10 control subjects. To determine diurnal and day-to-day variation, muscle strength was measured 4 times during day 1 and once at day 2.
RESULTS: Knee extension strength decreased during the day in both patients and controls. Neither diurnal nor day-to-day variation of muscle strength was higher in patients compared with controls.
CONCLUSIONS: Patients with mild to moderate MG did not have increased variation of isometric muscle strength during the day or from day-to-day compared with controls. This suggests that isometric muscle performance can be determined with high reproducibility in similar groups of MG patients without regard to time of day.
Originalsprog | Engelsk |
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Tidsskrift | Muscle & Nerve |
Vol/bind | 53 |
Udgave nummer | 1 |
Sider (fra-til) | 67-72 |
Antal sider | 6 |
ISSN | 0148-639X |
DOI | |
Status | Udgivet - jan. 2016 |
Udgivet eksternt | Ja |