Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?

Meena Asmar, Michael Bache, Filip K Knop, Sten Madsbad, Jens Juul Holst

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36 Citationer (Scopus)

Abstract

Amylin, cosecreted with insulin, has like glucagon-like peptide-1 (GLP-1) been reported to inhibit glucagon secretion, delay gastric emptying, and reduce appetite and food intake. We investigated whether the effects of GLP-1 on gastric emptying, appetite, and food intake are mediated directly or indirectly via release of amylin.
OriginalsprogEngelsk
TidsskriftThe Journal of clinical endocrinology and metabolism
Vol/bind95
Udgave nummer5
Sider (fra-til)2367-75
Antal sider9
DOI
StatusUdgivet - 1 maj 2010

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