@article{146a30aed92c4965bccb29126f50c239,
title = "Early detection of response to experimental chemotherapeutic Top216 with [18F]FLT and [18F]FDG PET in human ovary cancer xenografts in mice",
abstract = "3'-Deoxy-3'-[(18)F]fluorothymidine ((18)F-FLT) is a tracer used to assess cell proliferation in vivo. The aim of the study was to use (18)F-FLT positron emission tomography (PET) to study treatment responses to a new anti-cancer compound. To do so, we studied early anti-proliferative effects of the experimental chemotherapy Top216 non-invasively by PET.",
keywords = "Animals, Antineoplastic Agents, Cell Proliferation, Dideoxynucleosides, Disease Models, Animal, Drug Monitoring, Female, Fluorodeoxyglucose F18, Humans, Mice, Mice, Nude, Ovarian Neoplasms, Positron-Emission Tomography, Radiopharmaceuticals, Xenograft Model Antitumor Assays",
author = "Jensen, {Mette Munk} and Erichsen, {Kamille Dumong} and Fredrik Bj{\"o}rkling and Jacob Madsen and Jensen, {Peter Buhl} and Liselotte H{\o}jgaard and Maxwell Sehested and Andreas Kj{\ae}r",
year = "2010",
month = jan,
day = "1",
doi = "10.1371/journal.pone.0012965",
language = "English",
volume = "5",
pages = "e12965",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "9",
}