Abstract
Background: Only limited data have been published on the diagnostic accuracy of combining biparametric (bp) magnetic resonance imaging (MRI) and prostate-specific antigen density (PSAd) to rule out biopsies.
Purpose: The purpose is to assess the 2-year risk of being diagnosed with sPCa following the strategy of avoiding immediate biopsies in men with non-suspicious bp MRIs and a PSAd
Material and Methods: Two hundred biopsy-naive men with clinical suspicion of PCa underwent a pre-biopsy bp MRI from March to July 2019. Of these, 109 men had a Prostate Imaging Reporting and Data System (PI-RADS) score of 1-3 including 77 men with calculated PSAd = 0.15 ng/mL(2) underwent systematic biopsies and targeted biopsies of any PI-RADS 3 lesion.
Results: One of the 77 men (1.3%) had an sPCa diagnosed within 2 years of follow-up. All men were referred back to their general practitioner within 1 year and 9% (7/77) were re-referred to the urology department during follow-up. Among these men, 43% (3/7) continued to have PSA levels that were above their individual thresholds at confirmatory testing and underwent secondary MRI scans.
Conclusions: No biopsies for men with bpMRI results exhibiting maximum PI-RADS 3 and with a PSAd
Originalsprog | Engelsk |
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Artikelnummer | 20584601221094825 |
Tidsskrift | Acta Radiologica Open |
Vol/bind | 11 |
Udgave nummer | 4 |
Antal sider | 9 |
ISSN | 2047-9816 |
DOI | |
Status | Udgivet - 2022 |