Effect of lifelong resveratrol supplementation and exercise training on skeletal muscle oxidative capacity in aging mice: impact of PGC-1α

Stine  Ringholm; Jesper Olesen; Jesper Thorhauge Pedersen; Christina Tingbjerg Brandt; Jens Frey Halling; Ylva Hellsten; Clara Prats Gavalda; Henriette Pilegaard

doi:10.1016/j.exger.2013.08.012

Effect of lifelong resveratrol supplementation and exercise training on skeletal muscle oxidative capacity in aging mice: impact of PGC-1α

Stine Ringholm, Jesper Olesen, Jesper Thorhauge Pedersen, Christina Tingbjerg Brandt, Jens Frey Halling, Ylva Hellsten, Clara Prats Gavalda, Henriette Pilegaard

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

53 Citationer (Scopus)

Abstract

The present study tested the hypothesis that lifelong resveratrol (RSV) supplementation counteracts an age-associated decrease in skeletal muscle oxidative capacity through peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α and that RSV combined with lifelong exercise training (ET) exerts additive effects through PGC-1α in mice.

Originalsprog	Engelsk
Tidsskrift	Experimental Gerontology
Vol/bind	48
Udgave nummer	11
Sider (fra-til)	1311-1318
Antal sider	8
ISSN	0531-5565
DOI	https://doi.org/10.1016/j.exger.2013.08.012
Status	Udgivet - 2013

Bibliografisk note

CURIS 2013 NEXS 225

Adgang til dokumentet

10.1016/j.exger.2013.08.012

Citationsformater

Effect of lifelong resveratrol supplementation and exercise training on skeletal muscle oxidative capacity in aging mice : impact of PGC-1α. / Ringholm, Stine ; Olesen, Jesper; Pedersen, Jesper Thorhauge; Brandt, Christina Tingbjerg; Halling, Jens Frey; Hellsten, Ylva ; Prats Gavalda, Clara ; Pilegaard, Henriette.

I: Experimental Gerontology, Bind 48, Nr. 11, 2013, s. 1311-1318.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Ringholm, Stine ; Olesen, Jesper ; Pedersen, Jesper Thorhauge ; Brandt, Christina Tingbjerg ; Halling, Jens Frey ; Hellsten, Ylva ; Prats Gavalda, Clara ; Pilegaard, Henriette. / Effect of lifelong resveratrol supplementation and exercise training on skeletal muscle oxidative capacity in aging mice : impact of PGC-1α. I: Experimental Gerontology. 2013 ; Bind 48, Nr. 11. s. 1311-1318.

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abstract = "The present study tested the hypothesis that lifelong resveratrol (RSV) supplementation counteracts an age-associated decrease in skeletal muscle oxidative capacity through peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α and that RSV combined with lifelong exercise training (ET) exerts additive effects through PGC-1α in mice.",

author = "Stine Ringholm and Jesper Olesen and Pedersen, {Jesper Thorhauge} and Brandt, {Christina Tingbjerg} and Halling, {Jens Frey} and Ylva Hellsten and {Prats Gavalda}, Clara and Henriette Pilegaard",

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T2 - impact of PGC-1α

AU - Ringholm, Stine

AU - Olesen, Jesper

AU - Pedersen, Jesper Thorhauge

AU - Brandt, Christina Tingbjerg

AU - Halling, Jens Frey

AU - Hellsten, Ylva

AU - Prats Gavalda, Clara

AU - Pilegaard, Henriette

N1 - CURIS 2013 NEXS 225

PY - 2013

Y1 - 2013

N2 - The present study tested the hypothesis that lifelong resveratrol (RSV) supplementation counteracts an age-associated decrease in skeletal muscle oxidative capacity through peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α and that RSV combined with lifelong exercise training (ET) exerts additive effects through PGC-1α in mice.

AB - The present study tested the hypothesis that lifelong resveratrol (RSV) supplementation counteracts an age-associated decrease in skeletal muscle oxidative capacity through peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α and that RSV combined with lifelong exercise training (ET) exerts additive effects through PGC-1α in mice.

U2 - 10.1016/j.exger.2013.08.012

DO - 10.1016/j.exger.2013.08.012

M3 - Journal article

C2 - 23994519

VL - 48

SP - 1311

EP - 1318

JO - Experimental Gerontology

JF - Experimental Gerontology

SN - 0531-5565

IS - 11

ER -