Effects of insulin detemir and NPH insulin on renal handling of sodium, fluid retention and weight in type 2 diabetic patients

K V Hendriksen; Tonny Joran Jensen; P Oturai; B Feldt-Rasmussen

doi:10.1007/s00125-011-2345-8

Effects of insulin detemir and NPH insulin on renal handling of sodium, fluid retention and weight in type 2 diabetic patients

K V Hendriksen, Tonny Joran Jensen, P Oturai, B Feldt-Rasmussen

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

8 Citationer (Scopus)

Abstract

In type 2 diabetic patients, insulin detemir (B29Lys(ε-tetradecanoyl),desB30 human insulin) induces less weight gain than NPH insulin. Due to the proposed reduction of tubular action by insulin detemir, type 2 diabetic patients should have increased urinary sodium excretion, thereby reducing extracellular volume and body weight when changed from NPH insulin to insulin detemir.

Originalsprog	Engelsk
Tidsskrift	Diabetologia
Vol/bind	55
Udgave nummer	1
Sider (fra-til)	46-50
Antal sider	5
ISSN	0012-186X
DOI	https://doi.org/10.1007/s00125-011-2345-8
Status	Udgivet - 2012

Adgang til dokumentet

10.1007/s00125-011-2345-8

Citationsformater

@article{1d61ef9e7dce4a6d972844af1240a700,

title = "Effects of insulin detemir and NPH insulin on renal handling of sodium, fluid retention and weight in type 2 diabetic patients",

abstract = "In type 2 diabetic patients, insulin detemir (B29Lys(ε-tetradecanoyl),desB30 human insulin) induces less weight gain than NPH insulin. Due to the proposed reduction of tubular action by insulin detemir, type 2 diabetic patients should have increased urinary sodium excretion, thereby reducing extracellular volume and body weight when changed from NPH insulin to insulin detemir.",

author = "Hendriksen, {K V} and Jensen, {Tonny Joran} and P Oturai and B Feldt-Rasmussen",

year = "2012",

doi = "10.1007/s00125-011-2345-8",

language = "English",

volume = "55",

pages = "46--50",

journal = "Diabetologia",

issn = "0012-186X",

publisher = "Springer",

number = "1",

}

TY - JOUR

T1 - Effects of insulin detemir and NPH insulin on renal handling of sodium, fluid retention and weight in type 2 diabetic patients

AU - Hendriksen, K V

AU - Jensen, Tonny Joran

AU - Oturai, P

AU - Feldt-Rasmussen, B

PY - 2012

Y1 - 2012

N2 - In type 2 diabetic patients, insulin detemir (B29Lys(ε-tetradecanoyl),desB30 human insulin) induces less weight gain than NPH insulin. Due to the proposed reduction of tubular action by insulin detemir, type 2 diabetic patients should have increased urinary sodium excretion, thereby reducing extracellular volume and body weight when changed from NPH insulin to insulin detemir.

AB - In type 2 diabetic patients, insulin detemir (B29Lys(ε-tetradecanoyl),desB30 human insulin) induces less weight gain than NPH insulin. Due to the proposed reduction of tubular action by insulin detemir, type 2 diabetic patients should have increased urinary sodium excretion, thereby reducing extracellular volume and body weight when changed from NPH insulin to insulin detemir.

U2 - 10.1007/s00125-011-2345-8

DO - 10.1007/s00125-011-2345-8

M3 - Journal article

C2 - 22002075

VL - 55

SP - 46

EP - 50

JO - Diabetologia

JF - Diabetologia

SN - 0012-186X

IS - 1

ER -