Abstract
The Y chromosome usually plays a critical role in determining male sex and comprises sequence classes that have experienced unique evolutionary trajectories. Here we generated 19 new primate sex chromosome assemblies, analysed them with 10 existing assemblies and report rapid evolution of the Y chromosome across primates. The pseudoautosomal boundary has shifted at least six times during primate evolution, leading to the formation of a Simiiformes-specific evolutionary stratum and to the independent start of young strata in Catarrhini and Platyrrhini. Different primate lineages experienced different rates of gene loss and structural and chromatin change on their Y chromosomes. Selection on several Y-linked genes has contributed to the evolution of male developmental traits across the primates. Additionally, lineage-specific expansions of ampliconic regions have further increased the diversification of the structure and gene composition of the Y chromosome. Overall, our comprehensive analysis has broadened our knowledge of the evolution of the primate Y chromosome.
Originalsprog | Engelsk |
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Tidsskrift | Nature Ecology and Evolution |
Vol/bind | 7 |
Antal sider | 20 |
ISSN | 2397-334X |
DOI | |
Status | Udgivet - 2023 |
Bibliografisk note
Funding Information:We thank all supervisors, collaborators and anyone else involved with the collection and processing of the primary datasets. We thank China National GeneBank for providing the computational resources. This study was supported by grants from Strategic Priority Research Program of the Chinese Academy of Sciences (XDB31020000 to G.Z.), International Partnership Program of Chinese Academy of Sciences (no. 152453KYSB20170002 to G.Z.), Villum Investigator Grant (no. 25900 to G.Z.), National Natural Science Foundation of China (31822048 to D.-D.W.), Yunnan Fundamental Research Project (2019FI010 to D.-D.W.) and The Animal Branch of the Germplasm Bank of Wild Species of Chinese Academy of Science (the Large Research Infrastructure Funding to D.-D.W.).
Publisher Copyright:
© 2023, The Author(s), under exclusive licence to Springer Nature Limited.