Elevated transferrin saturation and risk of diabetes: Three population-based studies

Christina Ellervik, Thomas Mandrup-Poulsen, Henrik Ullits Andersen, Anne Tybjærg-Hansen, Merete Frandsen, Henrik Birgens, Børge G Nordestgaard

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45 Citationer (Scopus)

Abstract

OBJECTIVE We tested the hypothesis that elevated transferrin saturation is associated with an increased risk of any form of diabetes, as well as type 1 or type 2 diabetes separately. RESEARCH DESIGN AND METHODS We used two general population studies, The Copenhagen City Heart Study (CCHS, N = 9,121) and The Copenhagen General Population Study (CGPS, N = 24,195), as well as a 1:1 age- and sex-matched population-based case-control study with 6,129 patients with diabetes from the Steno Diabetes Centre and 6,129 control subjects, totaling 8,535 patients with diabetes and 37,039 control subjects. RESULTS In the combined studies, odds ratios in those with transferrin saturation =50% vs.
OriginalsprogEngelsk
TidsskriftDiabetes Care
Vol/bind34
Udgave nummer10
Sider (fra-til)2256-8
Antal sider3
ISSN0149-5992
DOI
StatusUdgivet - 2011

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