TY - JOUR
T1 - Elevated transferrin saturation and risk of diabetes
T2 - Three population-based studies
AU - Ellervik, Christina
AU - Mandrup-Poulsen, Thomas
AU - Andersen, Henrik Ullits
AU - Tybjærg-Hansen, Anne
AU - Frandsen, Merete
AU - Birgens, Henrik
AU - Nordestgaard, Børge G
PY - 2011
Y1 - 2011
N2 - OBJECTIVE We tested the hypothesis that elevated transferrin saturation is associated with an increased risk of any form of diabetes, as well as type 1 or type 2 diabetes separately. RESEARCH DESIGN AND METHODS We used two general population studies, The Copenhagen City Heart Study (CCHS, N = 9,121) and The Copenhagen General Population Study (CGPS, N = 24,195), as well as a 1:1 age- and sex-matched population-based case-control study with 6,129 patients with diabetes from the Steno Diabetes Centre and 6,129 control subjects, totaling 8,535 patients with diabetes and 37,039 control subjects. RESULTS In the combined studies, odds ratios in those with transferrin saturation =50% vs.
AB - OBJECTIVE We tested the hypothesis that elevated transferrin saturation is associated with an increased risk of any form of diabetes, as well as type 1 or type 2 diabetes separately. RESEARCH DESIGN AND METHODS We used two general population studies, The Copenhagen City Heart Study (CCHS, N = 9,121) and The Copenhagen General Population Study (CGPS, N = 24,195), as well as a 1:1 age- and sex-matched population-based case-control study with 6,129 patients with diabetes from the Steno Diabetes Centre and 6,129 control subjects, totaling 8,535 patients with diabetes and 37,039 control subjects. RESULTS In the combined studies, odds ratios in those with transferrin saturation =50% vs.
U2 - 10.2337/dc11-0416
DO - 10.2337/dc11-0416
M3 - Journal article
C2 - 21873562
VL - 34
SP - 2256
EP - 2258
JO - Diabetes Care
JF - Diabetes Care
SN - 0149-5992
IS - 10
ER -