Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo

Rikke N Haase; Rosette Megnekou; Maja Lundquist; Michael F Ofori; Lars Hviid; Trine Staalsoe

doi:10.1128/IAI.74.5.3035-3038.2006

Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo

Rikke N Haase, Rosette Megnekou, Maja Lundquist, Michael F Ofori, Lars Hviid, Trine Staalsoe

Centre for Medical Parasitology

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

49 Citationer (Scopus)

Abstract

Udgivelsesdato: 2006-May

Originalsprog	Engelsk
Tidsskrift	Infection and Immunity
Vol/bind	74
Udgave nummer	5
Sider (fra-til)	3035-8
Antal sider	3
ISSN	0019-9567
DOI	https://doi.org/10.1128/IAI.74.5.3035-3038.2006
Status	Udgivet - 2006

Bibliografisk note

Keywords: Animals; Antigens, Protozoan; CHO Cells; Cell Line, Tumor; Choriocarcinoma; Cricetinae; Erythrocytes; Female; Humans; Malaria, Falciparum; Placenta; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Uterine Neoplasms

Adgang til dokumentet

10.1128/IAI.74.5.3035-3038.2006

Citationsformater

Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo. / Haase, Rikke N; Megnekou, Rosette; Lundquist, Maja; Ofori, Michael F; Hviid, Lars; Staalsoe, Trine.

I: Infection and Immunity, Bind 74, Nr. 5, 2006, s. 3035-8.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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title = "Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo",

abstract = "Placenta-sequestering Plasmodium falciparum parasites causing pregnancy-associated malaria express pregnancy-specific variant surface antigens (VSA(PAM)). We report here that VSA(PAM)-expressing patient isolates adhere strongly to the choriocarcinoma cell line BeWo and that the BeWo line can be used to efficiently select for VSA(PAM) expression in vitro.",

author = "Haase, {Rikke N} and Rosette Megnekou and Maja Lundquist and Ofori, {Michael F} and Lars Hviid and Trine Staalsoe",

note = "Keywords: Animals; Antigens, Protozoan; CHO Cells; Cell Line, Tumor; Choriocarcinoma; Cricetinae; Erythrocytes; Female; Humans; Malaria, Falciparum; Placenta; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Uterine Neoplasms",

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T1 - Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo

AU - Haase, Rikke N

AU - Megnekou, Rosette

AU - Lundquist, Maja

AU - Ofori, Michael F

AU - Hviid, Lars

AU - Staalsoe, Trine

N1 - Keywords: Animals; Antigens, Protozoan; CHO Cells; Cell Line, Tumor; Choriocarcinoma; Cricetinae; Erythrocytes; Female; Humans; Malaria, Falciparum; Placenta; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Uterine Neoplasms

PY - 2006

Y1 - 2006

N2 - Placenta-sequestering Plasmodium falciparum parasites causing pregnancy-associated malaria express pregnancy-specific variant surface antigens (VSA(PAM)). We report here that VSA(PAM)-expressing patient isolates adhere strongly to the choriocarcinoma cell line BeWo and that the BeWo line can be used to efficiently select for VSA(PAM) expression in vitro.

AB - Placenta-sequestering Plasmodium falciparum parasites causing pregnancy-associated malaria express pregnancy-specific variant surface antigens (VSA(PAM)). We report here that VSA(PAM)-expressing patient isolates adhere strongly to the choriocarcinoma cell line BeWo and that the BeWo line can be used to efficiently select for VSA(PAM) expression in vitro.

U2 - 10.1128/IAI.74.5.3035-3038.2006

DO - 10.1128/IAI.74.5.3035-3038.2006

M3 - Journal article

C2 - 16622246

VL - 74

SP - 3035

EP - 3038

JO - Infection and Immunity

JF - Infection and Immunity

SN - 0019-9567

IS - 5

ER -