Endothelial function is unaffected by changing between carvedilol and metoprolol in patients with heart failure-a randomized study

Britt Falskov, Thomas Steffen Hermann, Jakob Raunsø, Buris Christiansen, Christian Rask-Madsen, Atheline Major-Pedersen, Lars Køber, Christian Torp-Pedersen, Maria Helena Dominguez Vall-Lamora, Britt Falskov

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    Abstract

    Carvedilol has been shown to be superior to metoprolol tartrate to improve clinical outcomes in patients with heart failure (HF), yet the mechanisms responsible for these differences remain unclear. We examined if there were differences in endothelial function, insulin stimulated endothelial function, 24 hour ambulatory blood pressure and heart rate during treatment with carvedilol, metoprolol tartrate and metoprolol succinate in patients with HF.
    OriginalsprogEngelsk
    TidsskriftCardiovascular Diabetology
    Vol/bind10
    Sider (fra-til)91
    ISSN1475-2840
    DOI
    StatusUdgivet - 2011

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