Engineering of an Inhalable DDA/TDB Liposomal Adjuvant: A Quality-by-Design Approach Towards Optimization of the Spray Drying Process

Pall Thor Ingvarsson; Mingshi Yang; Helle Mulvad; Hanne Mørck Nielsen; Jukka Rantanen; Camilla Foged

doi:10.1007/s11095-013-1096-2

Engineering of an Inhalable DDA/TDB Liposomal Adjuvant: A Quality-by-Design Approach Towards Optimization of the Spray Drying Process

Pall Thor Ingvarsson, Mingshi Yang, Helle Mulvad, Hanne Mørck Nielsen, Jukka Rantanen, Camilla Foged

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

46 Citationer (Scopus)

Abstract

The purpose of this study was to identify and optimize spray drying parameters of importance for the design of an inhalable powder formulation of a cationic liposomal adjuvant composed of dimethyldioctadecylammonium (DDA) bromide and trehalose-6,6'-dibehenate (TDB).

Originalsprog	Engelsk
Tidsskrift	Pharmaceutical Research
Vol/bind	30
Udgave nummer	11
Sider (fra-til)	2772-2784
ISSN	0724-8741
DOI	https://doi.org/10.1007/s11095-013-1096-2
Status	Udgivet - 22 jun. 2013

Adgang til dokumentet

10.1007/s11095-013-1096-2

Citationsformater

@article{3c08a6bb8e914161b0532e9ecf39bf37,

title = "Engineering of an Inhalable DDA/TDB Liposomal Adjuvant: A Quality-by-Design Approach Towards Optimization of the Spray Drying Process",

abstract = "The purpose of this study was to identify and optimize spray drying parameters of importance for the design of an inhalable powder formulation of a cationic liposomal adjuvant composed of dimethyldioctadecylammonium (DDA) bromide and trehalose-6,6'-dibehenate (TDB).",

author = "Ingvarsson, {Pall Thor} and Mingshi Yang and Helle Mulvad and Nielsen, {Hanne M{\o}rck} and Jukka Rantanen and Camilla Foged",

year = "2013",

month = jun,

day = "22",

doi = "10.1007/s11095-013-1096-2",

language = "English",

volume = "30",

pages = "2772--2784",

journal = "Pharmaceutical Research",

issn = "0724-8741",

publisher = "Springer",

number = "11",

}

TY - JOUR

T1 - Engineering of an Inhalable DDA/TDB Liposomal Adjuvant

T2 - A Quality-by-Design Approach Towards Optimization of the Spray Drying Process

AU - Ingvarsson, Pall Thor

AU - Yang, Mingshi

AU - Mulvad, Helle

AU - Nielsen, Hanne Mørck

AU - Rantanen, Jukka

AU - Foged, Camilla

PY - 2013/6/22

Y1 - 2013/6/22

N2 - The purpose of this study was to identify and optimize spray drying parameters of importance for the design of an inhalable powder formulation of a cationic liposomal adjuvant composed of dimethyldioctadecylammonium (DDA) bromide and trehalose-6,6'-dibehenate (TDB).

AB - The purpose of this study was to identify and optimize spray drying parameters of importance for the design of an inhalable powder formulation of a cationic liposomal adjuvant composed of dimethyldioctadecylammonium (DDA) bromide and trehalose-6,6'-dibehenate (TDB).

U2 - 10.1007/s11095-013-1096-2

DO - 10.1007/s11095-013-1096-2

M3 - Journal article

C2 - 23794038

SN - 0724-8741

VL - 30

SP - 2772

EP - 2784

JO - Pharmaceutical Research

JF - Pharmaceutical Research

IS - 11

ER -