Estimating GFR in children with 99mTc-DTPA renography: a comparison with single-sample 51Cr-EDTA clearance

Henrik Gutte; Michael L Møller; Andreas K Pfeifer; Jørgen Mogens Thorup; Line Borgwardt; Lise Borgwardt; Ulrik S Kristoffersen; Andreas Kjaer

doi:10.1111/j.1475-097X.2009.00910.x

Estimating GFR in children with 99mTc-DTPA renography: a comparison with single-sample 51Cr-EDTA clearance

Henrik Gutte, Michael L Møller, Andreas K Pfeifer, Jørgen Mogens Thorup, Line Borgwardt, Lise Borgwardt, Ulrik S Kristoffersen, Andreas Kjaer

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

19 Citationer (Scopus)

Abstract

Glomerular filtration rate (GFR) measurement by (51)Cr-ethylenediaminetetraacetic acid (EDTA) and blood sampling in children is usually cumbersome for the patient, parents and laboratory technicians. We have previously developed a method accurately estimating GFR in adults. The aim of the present study was to evaluate the accuracy of this non-invasive method in children. We calculated GFR from (99m)Tc-diethylene triamine pentaacetic acid (DTPA) renography and compared with (51)Cr-EDTA plasma clearance of 29 children between the age of 1 month and 12 years (mean 4.7 years). The correlation between (99m)Tc-DTPA renography and (51)Cr-EDTA plasma clearance was for all children R = 0.96 (n = 29, P

Originalsprog	Engelsk
Tidsskrift	Clinical Physiology and Functional Imaging
Vol/bind	30
Udgave nummer	3
Sider (fra-til)	169-74
Antal sider	6
ISSN	1475-0961
DOI	https://doi.org/10.1111/j.1475-097X.2009.00910.x
Status	Udgivet - 1 maj 2010

Adgang til dokumentet

10.1111/j.1475-097X.2009.00910.x

Citationsformater

Estimating GFR in children with 99mTc-DTPA renography: a comparison with single-sample 51Cr-EDTA clearance. / Gutte, Henrik; Møller, Michael L; Pfeifer, Andreas K; Thorup, Jørgen Mogens; Borgwardt, Line; Borgwardt, Lise; Kristoffersen, Ulrik S; Kjaer, Andreas.

I: Clinical Physiology and Functional Imaging, Bind 30, Nr. 3, 01.05.2010, s. 169-74.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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abstract = "Glomerular filtration rate (GFR) measurement by (51)Cr-ethylenediaminetetraacetic acid (EDTA) and blood sampling in children is usually cumbersome for the patient, parents and laboratory technicians. We have previously developed a method accurately estimating GFR in adults. The aim of the present study was to evaluate the accuracy of this non-invasive method in children. We calculated GFR from (99m)Tc-diethylene triamine pentaacetic acid (DTPA) renography and compared with (51)Cr-EDTA plasma clearance of 29 children between the age of 1 month and 12 years (mean 4.7 years). The correlation between (99m)Tc-DTPA renography and (51)Cr-EDTA plasma clearance was for all children R = 0.96 (n = 29, P",

keywords = "Child, Child, Preschool, Chromium Radioisotopes, Edetic Acid, Female, Glomerular Filtration Rate, Humans, Infant, Infant, Newborn, Kidney, Kidney Diseases, Male, Metabolic Clearance Rate, Radioisotope Renography, Radiopharmaceuticals, Reproducibility of Results, Sensitivity and Specificity, Technetium Tc 99m Pentetate",

author = "Henrik Gutte and M{\o}ller, {Michael L} and Pfeifer, {Andreas K} and Thorup, {J{\o}rgen Mogens} and Line Borgwardt and Lise Borgwardt and Kristoffersen, {Ulrik S} and Andreas Kjaer",

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AU - Gutte, Henrik

AU - Møller, Michael L

AU - Pfeifer, Andreas K

AU - Thorup, Jørgen Mogens

AU - Borgwardt, Line

AU - Borgwardt, Lise

AU - Kristoffersen, Ulrik S

AU - Kjaer, Andreas

PY - 2010/5/1

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N2 - Glomerular filtration rate (GFR) measurement by (51)Cr-ethylenediaminetetraacetic acid (EDTA) and blood sampling in children is usually cumbersome for the patient, parents and laboratory technicians. We have previously developed a method accurately estimating GFR in adults. The aim of the present study was to evaluate the accuracy of this non-invasive method in children. We calculated GFR from (99m)Tc-diethylene triamine pentaacetic acid (DTPA) renography and compared with (51)Cr-EDTA plasma clearance of 29 children between the age of 1 month and 12 years (mean 4.7 years). The correlation between (99m)Tc-DTPA renography and (51)Cr-EDTA plasma clearance was for all children R = 0.96 (n = 29, P

AB - Glomerular filtration rate (GFR) measurement by (51)Cr-ethylenediaminetetraacetic acid (EDTA) and blood sampling in children is usually cumbersome for the patient, parents and laboratory technicians. We have previously developed a method accurately estimating GFR in adults. The aim of the present study was to evaluate the accuracy of this non-invasive method in children. We calculated GFR from (99m)Tc-diethylene triamine pentaacetic acid (DTPA) renography and compared with (51)Cr-EDTA plasma clearance of 29 children between the age of 1 month and 12 years (mean 4.7 years). The correlation between (99m)Tc-DTPA renography and (51)Cr-EDTA plasma clearance was for all children R = 0.96 (n = 29, P

KW - Child

KW - Child, Preschool

KW - Chromium Radioisotopes

KW - Edetic Acid

KW - Female

KW - Glomerular Filtration Rate

KW - Humans

KW - Infant

KW - Infant, Newborn

KW - Kidney

KW - Kidney Diseases

KW - Male

KW - Metabolic Clearance Rate

KW - Radioisotope Renography

KW - Radiopharmaceuticals

KW - Reproducibility of Results

KW - Sensitivity and Specificity

KW - Technetium Tc 99m Pentetate

U2 - 10.1111/j.1475-097X.2009.00910.x

DO - 10.1111/j.1475-097X.2009.00910.x

M3 - Journal article

C2 - 20214666

VL - 30

SP - 169

EP - 174

JO - Clinical Physiology and Functional Imaging

JF - Clinical Physiology and Functional Imaging

SN - 1475-0961

IS - 3

ER -