Exercise training in older patients with systolic heart failure: Adherence, exercise capacity, inflammation and glycemic control

Eva Prescott; Rasmus Hjardem-Hansen; Flemming Dela; Ane Teisner; Henrik Nielsen

doi:10.1080/14017430802593427

Exercise training in older patients with systolic heart failure: Adherence, exercise capacity, inflammation and glycemic control

Eva Prescott, Rasmus Hjardem-Hansen, Flemming Dela, Ane Teisner, Henrik Nielsen

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

12 Citationer (Scopus)

Abstract

Udgivelsesdato: 2009

Originalsprog	Engelsk
Tidsskrift	Scandinavian Cardiovascular Journal
Vol/bind	43
Sider (fra-til)	249-255
Antal sider	6
ISSN	1401-7431
DOI	https://doi.org/10.1080/14017430802593427
Status	Udgivet - 2009

Adgang til dokumentet

10.1080/14017430802593427

Citationsformater

@article{9cfe2100567b11de87b8000ea68e967b,

title = "Exercise training in older patients with systolic heart failure: Adherence, exercise capacity, inflammation and glycemic control",

abstract = "Objectives. Training improves exercise capacity in patients with heart failure (CHF) but most evidence is on selected younger patients with systolic CHF. Design. All patients diagnosed with CHF over 3 years were screened for inclusion and exclusion criteria. Fifty two patients with systolic CHF (LVEF<45, NYHA II-III) received supervised exercise training twice weekly for 8 weeks. Results. Mean age was 68.2 (+/-SD 11.3) years. Despite marked improvements in physical fitness (workload, 6 minute walk test, incremental shuttle walk test and sit to stand test), there were no changes in serological markers of glycemic control (glucose, insulin, glycerol, free fatty acids, HbA1c), inflammation and endothelial function (hsCRP, orosomucoid, interleukin 6, TNF-alpha, urine-orosomucoid and -albumin/creatinin), lipid metabolism, NT-proBNP or other regulatory hormones (cortisol, epinephrine and IGF-1). There were no changes in quality of life. Conclusions. The effect of exercise training in these older CHF-patients was not as impressive as reported in younger and more selected patients. More studies on the efficiency of exercise training that reflect the age- and co-morbidity of the majority of CHF-patients are needed.",

author = "Eva Prescott and Rasmus Hjardem-Hansen and Flemming Dela and Ane Teisner and Henrik Nielsen",

year = "2009",

doi = "10.1080/14017430802593427",

language = "English",

volume = "43",

pages = "249--255",

journal = "Scandinavian Cardiovascular Journal",

issn = "1401-7431",

publisher = "Taylor & Francis",

}

TY - JOUR

T1 - Exercise training in older patients with systolic heart failure: Adherence, exercise capacity, inflammation and glycemic control

AU - Prescott, Eva

AU - Hjardem-Hansen, Rasmus

AU - Dela, Flemming

AU - Teisner, Ane

AU - Nielsen, Henrik

PY - 2009

Y1 - 2009

N2 - Objectives. Training improves exercise capacity in patients with heart failure (CHF) but most evidence is on selected younger patients with systolic CHF. Design. All patients diagnosed with CHF over 3 years were screened for inclusion and exclusion criteria. Fifty two patients with systolic CHF (LVEF<45, NYHA II-III) received supervised exercise training twice weekly for 8 weeks. Results. Mean age was 68.2 (+/-SD 11.3) years. Despite marked improvements in physical fitness (workload, 6 minute walk test, incremental shuttle walk test and sit to stand test), there were no changes in serological markers of glycemic control (glucose, insulin, glycerol, free fatty acids, HbA1c), inflammation and endothelial function (hsCRP, orosomucoid, interleukin 6, TNF-alpha, urine-orosomucoid and -albumin/creatinin), lipid metabolism, NT-proBNP or other regulatory hormones (cortisol, epinephrine and IGF-1). There were no changes in quality of life. Conclusions. The effect of exercise training in these older CHF-patients was not as impressive as reported in younger and more selected patients. More studies on the efficiency of exercise training that reflect the age- and co-morbidity of the majority of CHF-patients are needed.

AB - Objectives. Training improves exercise capacity in patients with heart failure (CHF) but most evidence is on selected younger patients with systolic CHF. Design. All patients diagnosed with CHF over 3 years were screened for inclusion and exclusion criteria. Fifty two patients with systolic CHF (LVEF<45, NYHA II-III) received supervised exercise training twice weekly for 8 weeks. Results. Mean age was 68.2 (+/-SD 11.3) years. Despite marked improvements in physical fitness (workload, 6 minute walk test, incremental shuttle walk test and sit to stand test), there were no changes in serological markers of glycemic control (glucose, insulin, glycerol, free fatty acids, HbA1c), inflammation and endothelial function (hsCRP, orosomucoid, interleukin 6, TNF-alpha, urine-orosomucoid and -albumin/creatinin), lipid metabolism, NT-proBNP or other regulatory hormones (cortisol, epinephrine and IGF-1). There were no changes in quality of life. Conclusions. The effect of exercise training in these older CHF-patients was not as impressive as reported in younger and more selected patients. More studies on the efficiency of exercise training that reflect the age- and co-morbidity of the majority of CHF-patients are needed.

U2 - 10.1080/14017430802593427

DO - 10.1080/14017430802593427

M3 - Journal article

C2 - 19101855

SN - 1401-7431

VL - 43

SP - 249

EP - 255

JO - Scandinavian Cardiovascular Journal

JF - Scandinavian Cardiovascular Journal

ER -