TY - JOUR
T1 - Experts do not agree when to treat retinopathy of prematurity based on plus disease
AU - Slidsborg, Carina
AU - Forman, Julie Lyng
AU - Fielder, Alistar
AU - Crafoord, Sven
AU - Baggesen, Kirsten Lau
AU - Bangsgaard, Regitze
AU - Fledelius, Hans Callø
AU - Greisen, Gorm
AU - la Cour, Morten
PY - 2012
Y1 - 2012
N2 - ObjectivesTo investigate inter-reader agreement on five severity levels of central vascular changes (none, mild, moderate, severe pre-plus disease, plus disease) and aggressive posterior retinopathy of prematurity (ROP), and to see whether an unintended shift in indication for treatment occurred.MethodsFour international ROP readers participated. Before the grading of the photographs, the readers were informed that a high proportion of advanced ROP cases were included. In total, 243 photographs/948 quadrants were available from 136 infants. As a standard series of photographs was available, grading was performed under optimised conditions.ResultsThe four readers agreed on the quadrant scores of only 70 (7.38%) of the 948 quadrants-that is, on 1, 5, 15, 4 and 45 quadrants for scores 0, 1, 2, 3 and 4, respectively. The mean scores differed systematically between the readers (permutation test, p
AB - ObjectivesTo investigate inter-reader agreement on five severity levels of central vascular changes (none, mild, moderate, severe pre-plus disease, plus disease) and aggressive posterior retinopathy of prematurity (ROP), and to see whether an unintended shift in indication for treatment occurred.MethodsFour international ROP readers participated. Before the grading of the photographs, the readers were informed that a high proportion of advanced ROP cases were included. In total, 243 photographs/948 quadrants were available from 136 infants. As a standard series of photographs was available, grading was performed under optimised conditions.ResultsThe four readers agreed on the quadrant scores of only 70 (7.38%) of the 948 quadrants-that is, on 1, 5, 15, 4 and 45 quadrants for scores 0, 1, 2, 3 and 4, respectively. The mean scores differed systematically between the readers (permutation test, p
U2 - 10.1136/bjophthalmol-2011-300573
DO - 10.1136/bjophthalmol-2011-300573
M3 - Journal article
C2 - 22174097
VL - 96
SP - 549
EP - 553
JO - British Journal of Ophthalmology
JF - British Journal of Ophthalmology
SN - 0007-1161
IS - 4
ER -