Expression of variant surface antigens by Plasmodium falciparum parasites in the peripheral blood of clinically immune pregnant women indicates ongoing placental infection

Michael F Ofori; Trine Staalsoe; Victoria Bam; Maja Lundquist; Kim P David; Edmund N L Browne; Bartholomew D Akanmori; Lars Hviid

Expression of variant surface antigens by Plasmodium falciparum parasites in the peripheral blood of clinically immune pregnant women indicates ongoing placental infection

Michael F Ofori, Trine Staalsoe, Victoria Bam, Maja Lundquist, Kim P David, Edmund N L Browne, Bartholomew D Akanmori, Lars Hviid

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

33 Citationer (Scopus)

Abstract

Udgivelsesdato: 2003-Mar

Originalsprog	Engelsk
Tidsskrift	Infection and Immunity
Vol/bind	71
Udgave nummer	3
Sider (fra-til)	1584-6
Antal sider	2
ISSN	0019-9567
Status	Udgivet - 2003

Bibliografisk note

Keywords: Animals; Antibodies, Protozoan; Antigens, Protozoan; Antigens, Surface; Female; Humans; Immunoglobulin G; Malaria, Falciparum; Placenta; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic

Citationsformater

Expression of variant surface antigens by Plasmodium falciparum parasites in the peripheral blood of clinically immune pregnant women indicates ongoing placental infection. / Ofori, Michael F; Staalsoe, Trine; Bam, Victoria; Lundquist, Maja; David, Kim P; Browne, Edmund N L; Akanmori, Bartholomew D; Hviid, Lars.

I: Infection and Immunity, Bind 71, Nr. 3, 2003, s. 1584-6.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Ofori, Michael F ; Staalsoe, Trine ; Bam, Victoria ; Lundquist, Maja ; David, Kim P ; Browne, Edmund N L ; Akanmori, Bartholomew D ; Hviid, Lars. / Expression of variant surface antigens by Plasmodium falciparum parasites in the peripheral blood of clinically immune pregnant women indicates ongoing placental infection. I: Infection and Immunity. 2003 ; Bind 71, Nr. 3. s. 1584-6.

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title = "Expression of variant surface antigens by Plasmodium falciparum parasites in the peripheral blood of clinically immune pregnant women indicates ongoing placental infection",

abstract = "Placenta-sequestered Plasmodium falciparum parasites that cause pregnancy-associated malaria (PAM) in otherwise clinically immune women express distinct variant surface antigens (VSA(PAM)) not expressed by parasites in nonpregnant individuals. We report here that parasites from the peripheral blood of clinically immune pregnant women also express VSA(PAM), making them a convenient source of VSA(PAM) expressors for PAM vaccine research.",

author = "Ofori, {Michael F} and Trine Staalsoe and Victoria Bam and Maja Lundquist and David, {Kim P} and Browne, {Edmund N L} and Akanmori, {Bartholomew D} and Lars Hviid",

note = "Keywords: Animals; Antibodies, Protozoan; Antigens, Protozoan; Antigens, Surface; Female; Humans; Immunoglobulin G; Malaria, Falciparum; Placenta; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic",

year = "2003",

language = "English",

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T1 - Expression of variant surface antigens by Plasmodium falciparum parasites in the peripheral blood of clinically immune pregnant women indicates ongoing placental infection

AU - Ofori, Michael F

AU - Staalsoe, Trine

AU - Bam, Victoria

AU - Lundquist, Maja

AU - David, Kim P

AU - Browne, Edmund N L

AU - Akanmori, Bartholomew D

AU - Hviid, Lars

N1 - Keywords: Animals; Antibodies, Protozoan; Antigens, Protozoan; Antigens, Surface; Female; Humans; Immunoglobulin G; Malaria, Falciparum; Placenta; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic

PY - 2003

Y1 - 2003

N2 - Placenta-sequestered Plasmodium falciparum parasites that cause pregnancy-associated malaria (PAM) in otherwise clinically immune women express distinct variant surface antigens (VSA(PAM)) not expressed by parasites in nonpregnant individuals. We report here that parasites from the peripheral blood of clinically immune pregnant women also express VSA(PAM), making them a convenient source of VSA(PAM) expressors for PAM vaccine research.

AB - Placenta-sequestered Plasmodium falciparum parasites that cause pregnancy-associated malaria (PAM) in otherwise clinically immune women express distinct variant surface antigens (VSA(PAM)) not expressed by parasites in nonpregnant individuals. We report here that parasites from the peripheral blood of clinically immune pregnant women also express VSA(PAM), making them a convenient source of VSA(PAM) expressors for PAM vaccine research.

M3 - Journal article

C2 - 12595482

VL - 71

SP - 1584

EP - 1586

JO - Infection and Immunity

JF - Infection and Immunity

SN - 0019-9567

IS - 3

ER -