ExTopoDB: a database of experimentally derived topological models of transmembrane proteins

Georgios N Tsaousis; Konstantinos D Tsirigos; Xanthi D Andrianou; Theodore D Liakopoulos; Pantelis G Bagos; Stavros J Hamodrakas

doi:10.1093/bioinformatics/btq362

ExTopoDB: a database of experimentally derived topological models of transmembrane proteins

Georgios N Tsaousis, Konstantinos D Tsirigos, Xanthi D Andrianou, Theodore D Liakopoulos, Pantelis G Bagos, Stavros J Hamodrakas

Brunak Group

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

18 Citationer (Scopus)

Abstract

UNLABELLED: ExTopoDB is a publicly accessible database of experimentally derived topological models of transmembrane proteins. It contains information collected from studies in the literature that report the use of biochemical methods for the determination of the topology of α-helical transmembrane proteins. Transmembrane protein topology is highly important in order to understand their function and ExTopoDB provides an up to date, complete and comprehensive dataset of experimentally determined topologies of α-helical transmembrane proteins. Topological information is combined with transmembrane topology prediction resulting in more reliable topological models.

AVAILABILITY: http://bioinformatics.biol.uoa.gr/ExTopoDB.

Originalsprog	Engelsk
Tidsskrift	Bioinformatics (Oxford, England)
Vol/bind	26
Udgave nummer	19
Sider (fra-til)	2490-2
Antal sider	3
ISSN	1367-4811
DOI	https://doi.org/10.1093/bioinformatics/btq362
Status	Udgivet - 1 okt. 2010

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Citationsformater

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abstract = "UNLABELLED: ExTopoDB is a publicly accessible database of experimentally derived topological models of transmembrane proteins. It contains information collected from studies in the literature that report the use of biochemical methods for the determination of the topology of α-helical transmembrane proteins. Transmembrane protein topology is highly important in order to understand their function and ExTopoDB provides an up to date, complete and comprehensive dataset of experimentally determined topologies of α-helical transmembrane proteins. Topological information is combined with transmembrane topology prediction resulting in more reliable topological models.AVAILABILITY: http://bioinformatics.biol.uoa.gr/ExTopoDB.",

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author = "Tsaousis, {Georgios N} and Tsirigos, {Konstantinos D} and Andrianou, {Xanthi D} and Liakopoulos, {Theodore D} and Bagos, {Pantelis G} and Hamodrakas, {Stavros J}",

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T2 - a database of experimentally derived topological models of transmembrane proteins

AU - Tsaousis, Georgios N

AU - Tsirigos, Konstantinos D

AU - Andrianou, Xanthi D

AU - Liakopoulos, Theodore D

AU - Bagos, Pantelis G

AU - Hamodrakas, Stavros J

PY - 2010/10/1

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N2 - UNLABELLED: ExTopoDB is a publicly accessible database of experimentally derived topological models of transmembrane proteins. It contains information collected from studies in the literature that report the use of biochemical methods for the determination of the topology of α-helical transmembrane proteins. Transmembrane protein topology is highly important in order to understand their function and ExTopoDB provides an up to date, complete and comprehensive dataset of experimentally determined topologies of α-helical transmembrane proteins. Topological information is combined with transmembrane topology prediction resulting in more reliable topological models.AVAILABILITY: http://bioinformatics.biol.uoa.gr/ExTopoDB.

AB - UNLABELLED: ExTopoDB is a publicly accessible database of experimentally derived topological models of transmembrane proteins. It contains information collected from studies in the literature that report the use of biochemical methods for the determination of the topology of α-helical transmembrane proteins. Transmembrane protein topology is highly important in order to understand their function and ExTopoDB provides an up to date, complete and comprehensive dataset of experimentally determined topologies of α-helical transmembrane proteins. Topological information is combined with transmembrane topology prediction resulting in more reliable topological models.AVAILABILITY: http://bioinformatics.biol.uoa.gr/ExTopoDB.

KW - Databases, Protein

KW - Membrane Proteins/chemistry

KW - Protein Conformation

KW - Sequence Analysis, Protein

KW - Software

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DO - 10.1093/bioinformatics/btq362

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SP - 2490

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JO - Bioinformatics (Oxford, England)

JF - Bioinformatics (Oxford, England)

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