Functional consequences of integrin gene mutations in mice.

D Bouvard; C Brakebusch; E Gustafsson; A Aszódi; T Bengtsson; A Berna; R Fässler

Functional consequences of integrin gene mutations in mice.

D Bouvard, C Brakebusch, E Gustafsson, A Aszódi, T Bengtsson, A Berna, R Fässler

Biomedicinsk Institut

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

201 Citationer (Scopus)

Abstract

Udgivelsesdato: 2001-Aug-3

Originalsprog	Engelsk
Tidsskrift	Circulation Research
Vol/bind	89
Udgave nummer	3
Sider (fra-til)	211-23
Antal sider	12
Status	Udgivet - 2001

Bibliografisk note

Keywords: Animals; Cell Migration Inhibition; Embryonic and Fetal Development; Genes, Lethal; Hematopoiesis; Hemostasis; Integrins; Leukocytes; Ligands; Mice; Mice, Mutant Strains; Mutation; Neovascularization, Physiologic; Phenotype; Signal Transduction

Citationsformater

@article{b234aca0589911dd8d9f000ea68e967b,

title = "Functional consequences of integrin gene mutations in mice.",

abstract = "Integrins are cell-surface receptors responsible for cell attachment to extracellular matrices and to other cells. The application of mouse genetics has significantly increased our understanding of integrin function in vivo. In this review, we summarize the phenotypes of mice carrying mutant integrin genes and compare them with phenotypes of mice lacking the integrin ligands.",

author = "D Bouvard and C Brakebusch and E Gustafsson and A Asz{\'o}di and T Bengtsson and A Berna and R F{\"a}ssler",

note = "Keywords: Animals; Cell Migration Inhibition; Embryonic and Fetal Development; Genes, Lethal; Hematopoiesis; Hemostasis; Integrins; Leukocytes; Ligands; Mice; Mice, Mutant Strains; Mutation; Neovascularization, Physiologic; Phenotype; Signal Transduction",

year = "2001",

language = "English",

volume = "89",

pages = "211--23",

journal = "Circulation Research",

issn = "0009-7330",

publisher = "AHA/ASA",

number = "3",

}

TY - JOUR

T1 - Functional consequences of integrin gene mutations in mice.

AU - Bouvard, D

AU - Brakebusch, C

AU - Gustafsson, E

AU - Aszódi, A

AU - Bengtsson, T

AU - Berna, A

AU - Fässler, R

N1 - Keywords: Animals; Cell Migration Inhibition; Embryonic and Fetal Development; Genes, Lethal; Hematopoiesis; Hemostasis; Integrins; Leukocytes; Ligands; Mice; Mice, Mutant Strains; Mutation; Neovascularization, Physiologic; Phenotype; Signal Transduction

PY - 2001

Y1 - 2001

N2 - Integrins are cell-surface receptors responsible for cell attachment to extracellular matrices and to other cells. The application of mouse genetics has significantly increased our understanding of integrin function in vivo. In this review, we summarize the phenotypes of mice carrying mutant integrin genes and compare them with phenotypes of mice lacking the integrin ligands.

AB - Integrins are cell-surface receptors responsible for cell attachment to extracellular matrices and to other cells. The application of mouse genetics has significantly increased our understanding of integrin function in vivo. In this review, we summarize the phenotypes of mice carrying mutant integrin genes and compare them with phenotypes of mice lacking the integrin ligands.

M3 - Journal article

C2 - 11485971

VL - 89

SP - 211

EP - 223

JO - Circulation Research

JF - Circulation Research

SN - 0009-7330

IS - 3

ER -