TY - JOUR
T1 - Generation Healthy Kids
T2 - Protocol for a cluster-randomized controlled trial of a multi-component and multi-setting intervention to promote healthy weight and wellbeing in 6–11-year-old children in Denmark
AU - Thomsen, Louise T.
AU - Schmidt-Persson, Jesper
AU - Damsgaard, Camilla Trab
AU - Krustrup, Peter
AU - Grøntved, Anders
AU - Krølner, Rikke Fredenslund
AU - Nielsen, Glen
AU - Lundbye-Jensen, Jesper
AU - Skovgaard, Thomas
AU - Mølgaard, Christian
AU - Hansen, Anders Blædel Gottlieb
AU - Hoeeg, Didde
AU - Larsen, Malte Nejst
AU - Lund, Line
AU - Melby, Paulina Sander
AU - Pedersen, Natascha Holbæk
AU - Troelsen, Jens
AU - Nordsborg, Nikolai Baastrup
AU - Toft, Ulla
N1 - Funding Information:
The study is funded by the Novo Nordisk Foundation (www.novonordiskfonden.dk) by grant no. NNF22SA0077224 awarded to NBN (primary investigator), JT (co-primary investigator), UT, CTD, PK, AG, RFK, JLJ, GN, TS and CM. The protocol underwent external peer review. The funders played no role in design of the study, writing of this study protocol, nor in the decision to submit the protocol for publication. Furthermore, the funder will play no role in data collection, data analysis, interpretation of results nor in any decision to submit future publications from the study. The authors gratefully acknowledge all staff in the Generation Healthy Kids Study Group which at the time of submission include: Anna Eilersen (WP2), Anne Lykke Poulsen (study secretariat), Bat-El Menadeva Karpantschof (WP2, WP6), Bo Kousgaard Poulsen (communication team), Danielle N\u00F8rager Johansen (WP1), Dorte William Wedell-Wedellsborg (WP1), Frederik Holmegaard Jensen (WP2, WP6), Ida Foxvig (WP1), Inge Rasmussen (WP2), Jane J\u00F8rgensen (WP2), Jonas Vestergaard Nielsen (WP1), Kristian Levring Madsen (communication team), Kristian Overgaard (WP3), Kristine M. Kristensen (WP2), Lene Stevner (Good Clinical Practice coordinator), Line Kattai Ulrikkeholm (WP2), Louise A. S. Brautsch (WP5), Louise Stjerne Madsen (communication team), Maja Vilhelmsen (WP1), Maja Sulstad Johansen (WP4), Mette Lindholm Kurtzhals (WP3), Pia Sandfeld Melcher (WP3), Sofie Koch (WP1), and Tine Buch Andersen (WP1). We also acknowledge all student assistants and scientific interns assisting with data collection. Furthermore, we acknowledge the members of our International Scientific Advisory Board for important scientific input to the design and conduct of the study: Professor Emeritus Adrian Bauman (University of Sydney, Australia); professor Harry Rutter (Department of Social & Policy Sciences, University of Bath, United Kingdom), professor Carolyn Summerbell (Department of Sport and Exercise Sciences, Durham University, United Kingdom), professor Steve Gortmaker (Department of Social and Behavioral Sciences, Harvard School of Public Health, USA), professor Fr\u00F8ydis N. Vik (Department of Nutrition and Public Health, University of Agder, Norway), and professor Joan L. Duda (School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, United Kingdom).
Publisher Copyright:
Copyright: © 2024 Thomsen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2024
Y1 - 2024
N2 - Background Childhood obesity can have significant negative consequences for children’s wellbeing and long-term health. Prior school-based interventions to prevent child overweight and obesity have shown limited effects, highlighting the necessity for comprehensive approaches addressing complex drivers of childhood obesity. “Generation Healthy Kids” (GHK) is a multi-setting, multi-component intervention to promote healthy weight development, health and wellbeing in Danish children aged 6–11 years. This protocol describes the GHK main trial, which is a cluster-randomized trial evaluating effectiveness and implementation of the GHK intervention. Methods Twenty-four schools from the Capital, Zealand and Southern Denmark Regions are randomly allocated 1:1 to intervention or control. The intervention will run for two school years (18–20 months) from October 2023 to June 2025 and will include children in 1st–3rd grade (approx. n = 1,600). The intervention targets multiple settings, including families, schools, after-school clubs, and local communities. Within four focus areas–diet, physical activity, screen media use, and sleep habits–the intervention incorporates several fixed elements, including a school lunch program and three weekly sessions of physical activity at school. Furthermore, building on whole-systems thinking, the intervention encompasses co-created elements developed in collaboration with local stakeholders, e.g. municipalities, sports clubs and supermarkets. This part of the intervention emphasizes building local capacity and engagement to promote child health. Effectiveness data will be collected from participating children and families at baseline, and at the end of school year one (after 6–8 months) and school year two (after 18–20 months). The primary outcome is the change in fat mass, measured by air-displacement plethysmography, from baseline to end-of-study in the intervention group compared to the control group. This is supplemented with numerous secondary outcomes and other prespecified outcomes related to child health and wellbeing. Furthermore, thorough process evaluation will be performed. Discussion GHK combines evidence-based intervention elements targeting multiple settings with a whole-systems approach focusing on capacity building and stakeholder involvement. This novel approach holds promise as an innovative way to promote child health and wellbeing and prevent childhood obesity.
AB - Background Childhood obesity can have significant negative consequences for children’s wellbeing and long-term health. Prior school-based interventions to prevent child overweight and obesity have shown limited effects, highlighting the necessity for comprehensive approaches addressing complex drivers of childhood obesity. “Generation Healthy Kids” (GHK) is a multi-setting, multi-component intervention to promote healthy weight development, health and wellbeing in Danish children aged 6–11 years. This protocol describes the GHK main trial, which is a cluster-randomized trial evaluating effectiveness and implementation of the GHK intervention. Methods Twenty-four schools from the Capital, Zealand and Southern Denmark Regions are randomly allocated 1:1 to intervention or control. The intervention will run for two school years (18–20 months) from October 2023 to June 2025 and will include children in 1st–3rd grade (approx. n = 1,600). The intervention targets multiple settings, including families, schools, after-school clubs, and local communities. Within four focus areas–diet, physical activity, screen media use, and sleep habits–the intervention incorporates several fixed elements, including a school lunch program and three weekly sessions of physical activity at school. Furthermore, building on whole-systems thinking, the intervention encompasses co-created elements developed in collaboration with local stakeholders, e.g. municipalities, sports clubs and supermarkets. This part of the intervention emphasizes building local capacity and engagement to promote child health. Effectiveness data will be collected from participating children and families at baseline, and at the end of school year one (after 6–8 months) and school year two (after 18–20 months). The primary outcome is the change in fat mass, measured by air-displacement plethysmography, from baseline to end-of-study in the intervention group compared to the control group. This is supplemented with numerous secondary outcomes and other prespecified outcomes related to child health and wellbeing. Furthermore, thorough process evaluation will be performed. Discussion GHK combines evidence-based intervention elements targeting multiple settings with a whole-systems approach focusing on capacity building and stakeholder involvement. This novel approach holds promise as an innovative way to promote child health and wellbeing and prevent childhood obesity.
U2 - 10.1371/journal.pone.0308142
DO - 10.1371/journal.pone.0308142
M3 - Journal article
C2 - 39636875
AN - SCOPUS:85211601181
VL - 19
JO - PLoS ONE
JF - PLoS ONE
SN - 1932-6203
IS - 12
M1 - e0308142
ER -