Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium

Linda E Kelemen; Marc T Goodman; Valerie McGuire; Mary Anne Rossing; Penelope M Webb; Martin Köbel; Hoda Anton-Culver; Jonathan Beesley; Andrew Berchuck; Sony Brar; Michael E Carney; Jenny Chang-Claude; Georgia Chenevix-Trench; Daniel W Cramer; Julie M Cunningham; Richard A Dicioccio; Jennifer A Doherty; Douglas F Easton; Zachary S Fredericksen; Brooke L Fridley; Margaret A Gates; Simon A Gayther; Aleksandra Gentry-Maharaj; Estrid Høgdall; Susanne Krüger Kjaer; Galina Lurie; Usha Menon; Patricia G Moorman; Kirsten Moysich; Roberta B Ness; Rachel T Palmieri; Celeste L Pearce; Paul D P Pharoah; Susan J Ramus; Honglin Song; Daniel O Stram; Shelley S Tworoger; David Van Den Berg; Robert A Vierkant; Shan Wang-Gohrke; Alice S Whittemore; Lynne R Wilkens; Anna H Wu; Joellen M Schildkraut; Thomas A Sellers; Ellen L Goode; Australian Cancer Study (Ovarian Cancer) Study Group

doi:http://dx.doi.org/10.1158/1055-9965.EPI-09-1317

Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium

Linda E Kelemen, Marc T Goodman, Valerie McGuire, Mary Anne Rossing, Penelope M Webb, Martin Köbel, Hoda Anton-Culver, Jonathan Beesley, Andrew Berchuck, Sony Brar, Michael E Carney, Jenny Chang-Claude, Georgia Chenevix-Trench, Daniel W Cramer, Julie M Cunningham, Richard A Dicioccio, Jennifer A Doherty, Douglas F Easton, Zachary S Fredericksen, Brooke L FridleyMargaret A Gates, Simon A Gayther, Aleksandra Gentry-Maharaj, Estrid Høgdall, Susanne Krüger Kjaer, Galina Lurie, Usha Menon, Patricia G Moorman, Kirsten Moysich, Roberta B Ness, Rachel T Palmieri, Celeste L Pearce, Paul D P Pharoah, Susan J Ramus, Honglin Song, Daniel O Stram, Shelley S Tworoger, David Van Den Berg, Robert A Vierkant, Shan Wang-Gohrke, Alice S Whittemore, Lynne R Wilkens, Anna H Wu, Joellen M Schildkraut, Thomas A Sellers, Ellen L Goode, Australian Cancer Study (Ovarian Cancer) Study Group

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

24 Citationer (Scopus)

Abstract

We previously reported the risks of ovarian carcinoma for common polymorphisms in one-carbon transfer genes. We sought to replicate associations for DPYD rs1801265, DNMT3A rs13420827, MTHFD1 rs1950902, MTHFS rs17284990, and TYMS rs495139 with risk of ovarian carcinoma overall and to use the large sample of assembled cases to investigate associations by histologic type.

Originalsprog	Engelsk
Tidsskrift	Cancer Epidemiology, Biomarkers & Prevention
Vol/bind	19
Udgave nummer	7
Sider (fra-til)	1822-30
Antal sider	9
ISSN	1055-9965
DOI	https://doi.org/10.1158/1055-9965.EPI-09-1317
Status	Udgivet - 1 jul. 2010

Adgang til dokumentet

http://dx.doi.org/10.1158/1055-9965.EPI-09-1317

Citationsformater

Kelemen, L. E., Goodman, M. T., McGuire, V., Rossing, M. A., Webb, P. M., Köbel, M., Anton-Culver, H., Beesley, J., Berchuck, A., Brar, S., Carney, M. E., Chang-Claude, J., Chenevix-Trench, G., Cramer, D. W., Cunningham, J. M., Dicioccio, R. A., Doherty, J. A., Easton, D. F., Fredericksen, Z. S., ... Australian Cancer Study (Ovarian Cancer) Study Group (2010). Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium. Cancer Epidemiology, Biomarkers & Prevention, 19(7), 1822-30. https://doi.org/10.1158/1055-9965.EPI-09-1317

Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium. / Kelemen, Linda E; Goodman, Marc T; McGuire, Valerie; Rossing, Mary Anne; Webb, Penelope M; Köbel, Martin; Anton-Culver, Hoda; Beesley, Jonathan; Berchuck, Andrew; Brar, Sony; Carney, Michael E; Chang-Claude, Jenny; Chenevix-Trench, Georgia; Cramer, Daniel W; Cunningham, Julie M; Dicioccio, Richard A; Doherty, Jennifer A; Easton, Douglas F; Fredericksen, Zachary S; Fridley, Brooke L; Gates, Margaret A; Gayther, Simon A; Gentry-Maharaj, Aleksandra; Høgdall, Estrid; Kjaer, Susanne Krüger; Lurie, Galina; Menon, Usha; Moorman, Patricia G; Moysich, Kirsten; Ness, Roberta B; Palmieri, Rachel T; Pearce, Celeste L; Pharoah, Paul D P; Ramus, Susan J; Song, Honglin; Stram, Daniel O; Tworoger, Shelley S; Van Den Berg, David; Vierkant, Robert A; Wang-Gohrke, Shan; Whittemore, Alice S; Wilkens, Lynne R; Wu, Anna H; Schildkraut, Joellen M; Sellers, Thomas A; Goode, Ellen L; Australian Cancer Study (Ovarian Cancer) Study Group.

I: Cancer Epidemiology, Biomarkers & Prevention, Bind 19, Nr. 7, 01.07.2010, s. 1822-30.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Kelemen, LE, Goodman, MT, McGuire, V, Rossing, MA, Webb, PM, Köbel, M, Anton-Culver, H, Beesley, J, Berchuck, A, Brar, S, Carney, ME, Chang-Claude, J, Chenevix-Trench, G, Cramer, DW, Cunningham, JM, Dicioccio, RA, Doherty, JA, Easton, DF, Fredericksen, ZS, Fridley, BL, Gates, MA, Gayther, SA, Gentry-Maharaj, A, Høgdall, E, Kjaer, SK, Lurie, G, Menon, U, Moorman, PG, Moysich, K, Ness, RB, Palmieri, RT, Pearce, CL, Pharoah, PDP, Ramus, SJ, Song, H, Stram, DO, Tworoger, SS, Van Den Berg, D, Vierkant, RA, Wang-Gohrke, S, Whittemore, AS, Wilkens, LR, Wu, AH, Schildkraut, JM, Sellers, TA, Goode, EL & Australian Cancer Study (Ovarian Cancer) Study Group 2010, 'Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium', Cancer Epidemiology, Biomarkers & Prevention, bind 19, nr. 7, s. 1822-30. https://doi.org/10.1158/1055-9965.EPI-09-1317

Kelemen, Linda E ; Goodman, Marc T ; McGuire, Valerie ; Rossing, Mary Anne ; Webb, Penelope M ; Köbel, Martin ; Anton-Culver, Hoda ; Beesley, Jonathan ; Berchuck, Andrew ; Brar, Sony ; Carney, Michael E ; Chang-Claude, Jenny ; Chenevix-Trench, Georgia ; Cramer, Daniel W ; Cunningham, Julie M ; Dicioccio, Richard A ; Doherty, Jennifer A ; Easton, Douglas F ; Fredericksen, Zachary S ; Fridley, Brooke L ; Gates, Margaret A ; Gayther, Simon A ; Gentry-Maharaj, Aleksandra ; Høgdall, Estrid ; Kjaer, Susanne Krüger ; Lurie, Galina ; Menon, Usha ; Moorman, Patricia G ; Moysich, Kirsten ; Ness, Roberta B ; Palmieri, Rachel T ; Pearce, Celeste L ; Pharoah, Paul D P ; Ramus, Susan J ; Song, Honglin ; Stram, Daniel O ; Tworoger, Shelley S ; Van Den Berg, David ; Vierkant, Robert A ; Wang-Gohrke, Shan ; Whittemore, Alice S ; Wilkens, Lynne R ; Wu, Anna H ; Schildkraut, Joellen M ; Sellers, Thomas A ; Goode, Ellen L ; Australian Cancer Study (Ovarian Cancer) Study Group. / Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium. I: Cancer Epidemiology, Biomarkers & Prevention. 2010 ; Bind 19, Nr. 7. s. 1822-30.

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abstract = "We previously reported the risks of ovarian carcinoma for common polymorphisms in one-carbon transfer genes. We sought to replicate associations for DPYD rs1801265, DNMT3A rs13420827, MTHFD1 rs1950902, MTHFS rs17284990, and TYMS rs495139 with risk of ovarian carcinoma overall and to use the large sample of assembled cases to investigate associations by histologic type.",

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AU - Kelemen, Linda E

AU - Goodman, Marc T

AU - McGuire, Valerie

AU - Rossing, Mary Anne

AU - Webb, Penelope M

AU - Köbel, Martin

AU - Anton-Culver, Hoda

AU - Beesley, Jonathan

AU - Berchuck, Andrew

AU - Brar, Sony

AU - Carney, Michael E

AU - Chang-Claude, Jenny

AU - Chenevix-Trench, Georgia

AU - Cramer, Daniel W

AU - Cunningham, Julie M

AU - Dicioccio, Richard A

AU - Doherty, Jennifer A

AU - Easton, Douglas F

AU - Fredericksen, Zachary S

AU - Fridley, Brooke L

AU - Gates, Margaret A

AU - Gayther, Simon A

AU - Gentry-Maharaj, Aleksandra

AU - Høgdall, Estrid

AU - Kjaer, Susanne Krüger

AU - Lurie, Galina

AU - Menon, Usha

AU - Moorman, Patricia G

AU - Moysich, Kirsten

AU - Ness, Roberta B

AU - Palmieri, Rachel T

AU - Pearce, Celeste L

AU - Pharoah, Paul D P

AU - Ramus, Susan J

AU - Song, Honglin

AU - Stram, Daniel O

AU - Tworoger, Shelley S

AU - Van Den Berg, David

AU - Vierkant, Robert A

AU - Wang-Gohrke, Shan

AU - Whittemore, Alice S

AU - Wilkens, Lynne R

AU - Wu, Anna H

AU - Schildkraut, Joellen M

AU - Sellers, Thomas A

AU - Goode, Ellen L

AU - Australian Cancer Study (Ovarian Cancer) Study Group

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DO - http://dx.doi.org/10.1158/1055-9965.EPI-09-1317

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