Genetically engineered bacterium for the production of 3-hydroxybutyrate

Michael Koepke; Rasmus Overgaard Jensen; James Bruce Yarnton H Behrendorff; Ryan Edward Hill; Darmawi Juminaga; Alexander Paul Mueller

Genetically engineered bacterium for the production of 3-hydroxybutyrate

Michael Koepke (Opfinder)
, Rasmus Overgaard Jensen (Opfinder)
, James Bruce Yarnton H Behrendorff (Opfinder)
, Ryan Edward Hill (Opfinder)
, Darmawi Juminaga (Opfinder)
, Alexander Paul Mueller (Opfinder)

Publikation: Patent

Abstract

The invention relates to a genetically engineered bacterium having an enzyme that converts acetyl-CoA to acetoacetyl-CoA, an enzyme that converts acetoacetyl-CoA to 3-hydroxybutyryl-CoA, and an enzyme that converts 3-hydroxybutyryl-CoA to 3-hydroxybutyrate. The bacterium may also have enzymes to produce other downstream products, such as 3-hydroxybutyryaldehyde, and 1,3-butanediol. Typically, the bacterium is capable of producing these products from a gaseous substrate, such as syngas or an industrial waste gas.

Originalsprog	Engelsk
IPC	C12P7/42
Patentnummer	US9957531B1
Land/Område	Danmark
Prioritetsdato	13/10/2015
Status	Udgivet - 1 maj 2018
Udgivet eksternt	Ja

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title = "Genetically engineered bacterium for the production of 3-hydroxybutyrate",

abstract = "The invention relates to a genetically engineered bacterium having an enzyme that converts acetyl-CoA to acetoacetyl-CoA, an enzyme that converts acetoacetyl-CoA to 3-hydroxybutyryl-CoA, and an enzyme that converts 3-hydroxybutyryl-CoA to 3-hydroxybutyrate. The bacterium may also have enzymes to produce other downstream products, such as 3-hydroxybutyryaldehyde, and 1,3-butanediol. Typically, the bacterium is capable of producing these products from a gaseous substrate, such as syngas or an industrial waste gas.",

author = "Michael Koepke and Jensen, \{Rasmus Overgaard\} and Behrendorff, \{James Bruce Yarnton H\} and Hill, \{Ryan Edward\} and Darmawi Juminaga and Mueller, \{Alexander Paul\}",

year = "2018",

month = may,

day = "1",

language = "English",

type = "Patent",

note = "US9957531B1; C12P7/42",

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TY - PAT

T1 - Genetically engineered bacterium for the production of 3-hydroxybutyrate

AU - Koepke, Michael

AU - Jensen, Rasmus Overgaard

AU - Behrendorff, James Bruce Yarnton H

AU - Hill, Ryan Edward

AU - Juminaga, Darmawi

AU - Mueller, Alexander Paul

PY - 2018/5/1

Y1 - 2018/5/1

N2 - The invention relates to a genetically engineered bacterium having an enzyme that converts acetyl-CoA to acetoacetyl-CoA, an enzyme that converts acetoacetyl-CoA to 3-hydroxybutyryl-CoA, and an enzyme that converts 3-hydroxybutyryl-CoA to 3-hydroxybutyrate. The bacterium may also have enzymes to produce other downstream products, such as 3-hydroxybutyryaldehyde, and 1,3-butanediol. Typically, the bacterium is capable of producing these products from a gaseous substrate, such as syngas or an industrial waste gas.

AB - The invention relates to a genetically engineered bacterium having an enzyme that converts acetyl-CoA to acetoacetyl-CoA, an enzyme that converts acetoacetyl-CoA to 3-hydroxybutyryl-CoA, and an enzyme that converts 3-hydroxybutyryl-CoA to 3-hydroxybutyrate. The bacterium may also have enzymes to produce other downstream products, such as 3-hydroxybutyryaldehyde, and 1,3-butanediol. Typically, the bacterium is capable of producing these products from a gaseous substrate, such as syngas or an industrial waste gas.

M3 - Patent

M1 - US9957531B1

ER -