Genetically engineered microorganisms for the production of chorismate-derived products

James Bruce Yarnton H Behrendorff; Michael Koepke; Loan Phuong Tran; Wyatt Eric Allen

Genetically engineered microorganisms for the production of chorismate-derived products

James Bruce Yarnton H Behrendorff (Opfinder), Michael Koepke (Opfinder), Loan Phuong Tran (Opfinder), Wyatt Eric Allen (Opfinder)

Publikation: Patent

Abstract

The invention provides genetically engineered microorganisms and methods for producing chorismate-derived products, such as para-hydroxybenzoic acid, salicylate, 2-aminobenzoate, 2,3-dihydroxybenzoate, and 4-hydroxycyclohexane carboxylic acid. Typically, the microorganism comprises at least one of (a) an exogenous chorismate pyruvate lyase, (b) an exogenous isochorismate synthase, (c) an exogenous isochorismate pyruvate lyase, and (d) a prephenate synthase comprising a disruptive mutation.

Originalsprog	Engelsk
IPC	C12N9/88
Patentnummer	US20160348087A1
Land/Område	Danmark
Prioritetsnummer	27/05/2015
Status	Udgivet - 1 dec. 2016
Udgivet eksternt	Ja

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title = "Genetically engineered microorganisms for the production of chorismate-derived products",

abstract = "The invention provides genetically engineered microorganisms and methods for producing chorismate-derived products, such as para-hydroxybenzoic acid, salicylate, 2-aminobenzoate, 2,3-dihydroxybenzoate, and 4-hydroxycyclohexane carboxylic acid. Typically, the microorganism comprises at least one of (a) an exogenous chorismate pyruvate lyase, (b) an exogenous isochorismate synthase, (c) an exogenous isochorismate pyruvate lyase, and (d) a prephenate synthase comprising a disruptive mutation.",

author = "Behrendorff, {James Bruce Yarnton H} and Michael Koepke and Tran, {Loan Phuong} and Allen, {Wyatt Eric}",

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T1 - Genetically engineered microorganisms for the production of chorismate-derived products

AU - Behrendorff, James Bruce Yarnton H

AU - Koepke, Michael

AU - Tran, Loan Phuong

AU - Allen, Wyatt Eric

PY - 2016/12/1

Y1 - 2016/12/1

N2 - The invention provides genetically engineered microorganisms and methods for producing chorismate-derived products, such as para-hydroxybenzoic acid, salicylate, 2-aminobenzoate, 2,3-dihydroxybenzoate, and 4-hydroxycyclohexane carboxylic acid. Typically, the microorganism comprises at least one of (a) an exogenous chorismate pyruvate lyase, (b) an exogenous isochorismate synthase, (c) an exogenous isochorismate pyruvate lyase, and (d) a prephenate synthase comprising a disruptive mutation.

AB - The invention provides genetically engineered microorganisms and methods for producing chorismate-derived products, such as para-hydroxybenzoic acid, salicylate, 2-aminobenzoate, 2,3-dihydroxybenzoate, and 4-hydroxycyclohexane carboxylic acid. Typically, the microorganism comprises at least one of (a) an exogenous chorismate pyruvate lyase, (b) an exogenous isochorismate synthase, (c) an exogenous isochorismate pyruvate lyase, and (d) a prephenate synthase comprising a disruptive mutation.

M3 - Patent

M1 - US20160348087A1

ER -