Genetics of metabolic traits in Greenlanders

Anne Cathrine Baun Thuesen; Mette K. Andersen; Torben Hansen

Genetics of metabolic traits in Greenlanders

Anne Cathrine Baun Thuesen, Mette K. Andersen, Torben Hansen

Hansen Group

Publikation: Bidrag til tidsskrift › Review › Forskning › peer review

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Abstract

The history of the Greenlandic population has contributed to a unique genetic composition in which high-impact and often novel genetic variants segregate at a high frequency. As a result, research in smaller populations like the Greenlandic has the potential to reveal genetic variation and associations that are not present or discoverable in other populations. In this review, we provide a summary of our research in Greenlanders and our findings of genetic variants with high impact on metabolic health, and outline the implications that this research has for the equitable distribution of genomic precision medicine.

Originalsprog	Engelsk
Artikelnummer	A05230332
Tidsskrift	Danish Medical Journal
Vol/bind	70
Udgave nummer	12
Antal sider	9
ISSN	2245-1919
Status	Udgivet - 2023

Bibliografisk note

Publisher Copyright:
Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

Adgang til dokumentet

FulltextForlagets udgivne version, 657 KBLicens: CC BY-NC-ND

https://ugeskriftet.dk/dmj/genetics-metabolic-traits-greenlandersLicens: CC BY-NC-ND

Citationsformater

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title = "Genetics of metabolic traits in Greenlanders",

abstract = "The history of the Greenlandic population has contributed to a unique genetic composition in which high-impact and often novel genetic variants segregate at a high frequency. As a result, research in smaller populations like the Greenlandic has the potential to reveal genetic variation and associations that are not present or discoverable in other populations. In this review, we provide a summary of our research in Greenlanders and our findings of genetic variants with high impact on metabolic health, and outline the implications that this research has for the equitable distribution of genomic precision medicine.",

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AU - Thuesen, Anne Cathrine Baun

AU - Andersen, Mette K.

AU - Hansen, Torben

N1 - Publisher Copyright: Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2023

Y1 - 2023

N2 - The history of the Greenlandic population has contributed to a unique genetic composition in which high-impact and often novel genetic variants segregate at a high frequency. As a result, research in smaller populations like the Greenlandic has the potential to reveal genetic variation and associations that are not present or discoverable in other populations. In this review, we provide a summary of our research in Greenlanders and our findings of genetic variants with high impact on metabolic health, and outline the implications that this research has for the equitable distribution of genomic precision medicine.

AB - The history of the Greenlandic population has contributed to a unique genetic composition in which high-impact and often novel genetic variants segregate at a high frequency. As a result, research in smaller populations like the Greenlandic has the potential to reveal genetic variation and associations that are not present or discoverable in other populations. In this review, we provide a summary of our research in Greenlanders and our findings of genetic variants with high impact on metabolic health, and outline the implications that this research has for the equitable distribution of genomic precision medicine.

M3 - Review

C2 - 38018706

AN - SCOPUS:85178497385

VL - 70

JO - Danish Medical Journal

JF - Danish Medical Journal

SN - 2245-1919

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