Genomic Microevolution of Vibrio cholerae O1, Lake Tanganyika Basin, Africa

Yaovi M.G. Hounmanou, Elisabeth Njamkepo, Jean Rauzier, Karin Gallandat, Aurélie Jeandron, Guyguy Kamwiziku, Klaudia Porten, Francisco Luquero, Aaron Aruna Abedi, Baron Bashige Rumedeka, Berthe Miwanda, Martin Michael, Placide Welo Okitayemba, Jaime Mufitini Saidi, Renaud Piarroux, François Xavier Weill, Anders Dalsgaard, Marie Laure Quilici

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Abstract

Africa's Lake Tanganyika basin is a cholera hotspot. During 2001-2020, Vibrio cholerae O1 isolates obtained from the Democratic Republic of the Congo side of the lake belonged to 2 of the 5 clades of the AFR10 sublineage. One clade became predominant after acquiring a parC mutation that decreased susceptibility to ciprofloxacin.

OriginalsprogEngelsk
TidsskriftEmerging Infectious Diseases
Vol/bind29
Udgave nummer1
Sider (fra-til)149-153
Antal sider5
ISSN1080-6040
DOI
StatusUdgivet - 2023

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