Gestational Hypertension and High-Density Lipoprotein Function: An Explorative Study in Overweight/Obese Women of the DALI Cohort

Julia T. Stadler, M. N. M. van Poppel, Christina Christoffersen, David Hill, Christian Wadsack, David Simmons, Gernot Desoye, Gunther Marsche, DALI Core Investigator Grp

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

6 Citationer (Scopus)
13 Downloads (Pure)

Abstract

Gestational hypertension (GHTN) is associated with an increased cardiovascular risk for mothers and their offspring later in life. High-density lipoproteins (HDL) are anti-atherogenic by promoting efflux of cholesterol from macrophages and suppression of endothelial cell activation. Functional impairment of HDL in GHTN-complicated pregnancies may affect long-term health of both mothers and offspring. We studied functional parameters of maternal and neonatal HDL in 192 obese women (pre-pregnancy BMI >= 29), who were at high risk for GHTN. Maternal blood samples were collected longitudinally at

OriginalsprogEngelsk
Artikelnummer68
TidsskriftAntioxidants
Vol/bind12
Udgave nummer1
Antal sider13
ISSN2076-3921
DOI
StatusUdgivet - 2023

Citationsformater