Gruppe B-streptokokker hos nyfødte og i de første tre levemåneder

Ida Nikoline Mandic; Victoria Elizabeth de Knegt; Hristo Stanchev; Tine Brink Henriksen; Emma Louise Malchau Carlsen; Maren Johanne Heilskov Rytter

doi:10.61409/V01240022

Gruppe B-streptokokker hos nyfødte og i de første tre levemåneder

Ida Nikoline Mandic, Victoria Elizabeth de Knegt, Hristo Stanchev, Tine Brink Henriksen, Emma Louise Malchau Carlsen, Maren Johanne Heilskov Rytter

Publikation: Bidrag til tidsskrift › Review › peer review

1 Citationer (Scopus)

9 Downloads (Pure)

Abstract

Group B Streptococcus (GBS) disease in neonates occurs in two forms: early-onset disease (EOD), (day 0-6), and late-onset disease (LOD), (day 7-90). This review investigates that risk-based intrapartum screening and antibiotics have reduced the incidence of EOD, but not LOD, in Denmark. No clinical or laboratory tests can rule out GBS disease at symptom onset. Thus, a high proportion of uninfected infants receive antibiotics, although this varies widely, and may be reduced by strategies of antibiotic stewardship. A future GBS vaccine for pregnant women may potentially reduce disease burden and antibiotic exposure.

Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	186
Udgave nummer	26
Antal sider	7
ISSN	0041-5782
DOI	https://doi.org/10.61409/V01240022
Status	Udgivet - 2024

Bibliografisk note

Publisher Copyright:
Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

Adgang til dokumentet

10.61409/V01240022Licens: CC BY-NC-ND

FulltextForlagets udgivne version, 204 KBLicens: CC BY-NC-ND

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Citationsformater

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title = "Gruppe B-streptokokker hos nyf{\o}dte og i de f{\o}rste tre levem{\aa}neder",

abstract = "Group B Streptococcus (GBS) disease in neonates occurs in two forms: early-onset disease (EOD), (day 0-6), and late-onset disease (LOD), (day 7-90). This review investigates that risk-based intrapartum screening and antibiotics have reduced the incidence of EOD, but not LOD, in Denmark. No clinical or laboratory tests can rule out GBS disease at symptom onset. Thus, a high proportion of uninfected infants receive antibiotics, although this varies widely, and may be reduced by strategies of antibiotic stewardship. A future GBS vaccine for pregnant women may potentially reduce disease burden and antibiotic exposure.",

author = "Mandic, {Ida Nikoline} and {de Knegt}, {Victoria Elizabeth} and Hristo Stanchev and Henriksen, {Tine Brink} and Carlsen, {Emma Louise Malchau} and Rytter, {Maren Johanne Heilskov}",

note = "Publisher Copyright: Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.",

year = "2024",

doi = "10.61409/V01240022",

language = "Dansk",

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T1 - Gruppe B-streptokokker hos nyfødte og i de første tre levemåneder

AU - Mandic, Ida Nikoline

AU - de Knegt, Victoria Elizabeth

AU - Stanchev, Hristo

AU - Henriksen, Tine Brink

AU - Carlsen, Emma Louise Malchau

AU - Rytter, Maren Johanne Heilskov

N1 - Publisher Copyright: Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2024

Y1 - 2024

N2 - Group B Streptococcus (GBS) disease in neonates occurs in two forms: early-onset disease (EOD), (day 0-6), and late-onset disease (LOD), (day 7-90). This review investigates that risk-based intrapartum screening and antibiotics have reduced the incidence of EOD, but not LOD, in Denmark. No clinical or laboratory tests can rule out GBS disease at symptom onset. Thus, a high proportion of uninfected infants receive antibiotics, although this varies widely, and may be reduced by strategies of antibiotic stewardship. A future GBS vaccine for pregnant women may potentially reduce disease burden and antibiotic exposure.

AB - Group B Streptococcus (GBS) disease in neonates occurs in two forms: early-onset disease (EOD), (day 0-6), and late-onset disease (LOD), (day 7-90). This review investigates that risk-based intrapartum screening and antibiotics have reduced the incidence of EOD, but not LOD, in Denmark. No clinical or laboratory tests can rule out GBS disease at symptom onset. Thus, a high proportion of uninfected infants receive antibiotics, although this varies widely, and may be reduced by strategies of antibiotic stewardship. A future GBS vaccine for pregnant women may potentially reduce disease burden and antibiotic exposure.

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DO - 10.61409/V01240022

M3 - Review

C2 - 38953689

AN - SCOPUS:85197706909

SN - 0041-5782

VL - 186

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

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ER -