Hip strengthening exercise dosage is not associated with clinical improvements after total hip arthroplasty – a prospective cohort study (the PHETHAS-1 study)

Merete Nørgaard Madsen*, Lone Ramer Mikkelsen, Michael Skovdal Rathleff, Kristian Thorborg, Thomas Kallemose, Thomas Bandholm

*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstract

Background
Postoperative rehabilitation exercise is commonly prescribed after total hip arthroplasty (THA), but its efficacy compared to no or minimal rehabilitation exercise has been questioned. Preliminary efficacy would be indicated if a dose-response relationship exists between performed exercise dose and degree of postoperative recovery. The objective was to evaluate the preliminary efficacy of home-based rehabilitation using elastic band exercise on performance-based function after THA, based on the association between performed exercise dose and change in performance-based function (gait speed) from 3 (start of intervention) to 10 weeks (end of intervention) after surgery.

Methods
A prospective cohort study was conducted. Following primary THA, patients were prescribed home-based rehabilitation exercise using elastic bands. Performed exercise dose (repetitions/week) was objectively measured using attached sensor technology. Primary outcome was change in gait speed (40 m fast-paced walk test). Secondary outcomes included patient-reported hip disability. In the primary analysis, a linear regression model was used.

Results
Ninety-four patients (39 women) with a median age of 66.5 years performed a median of 339 exercise repetitions/week (1st-3rd quartile: 209–549). Across outcomes, participants significantly improved from 3 to 10-week follow-up. The association between performed exercise dose and change in mean gait speed was 0.01 m/s [95% CI: -0.01; 0.02] per 100 repetitions.

Conclusions
We found no indication of preliminary efficacy of home-based rehabilitation exercise using elastic bands, as no significant and clinically relevant associations between performed exercise dose and changes in outcomes were present. Trials comparing postoperative rehabilitation exercise with no exercise early after THA are warranted.

Trial registration
Pre-registered: ClinicalTrials.gov (Identifier: NCT03109821, 12/04/2017).
OriginalsprogEngelsk
Artikelnummer928
TidsskriftBMC Musculoskeletal Disorders
Vol/bind25
Udgave nummer1
Antal sider13
ISSN1471-2474
DOI
StatusUdgivet - 2024

Bibliografisk note

Funding Information:
The PHETHAS-1 study has received grants from: Regional Hospital Central Jutland Research Foundation, The Danish Rheumatism Association, The Association of Danish Physiotherapists, The Aase and Ejnar Danielsen Foundation and The family Kj\u00E6rsgaard foundation. Furthermore, the PHETHAS-1 study has become part of a PhD project, which has received funding from: Regional Hospital Central Jutland Research Foundation, The Danish Rheumatism Association, The Association of Danish Physiotherapists, The Faculty of Health, Aarhus University, The Department of Clinical Medicine, Aarhus University and The Frimodt-Heineke Foundation. The funding sources had no part in the design, conduction or reporting of the trial, thus there is no conflict of interests.

Funding Information:
The authors would like to thank physiotherapist, Rikke Dahl Nyholm and research assistant Trine Astrup Bech Vestergaard for their invaluable dedication, expertise and help throughout the research process. We would also like to thank the staff and chairs at The Elective Surgery Centre, Silkeborg Regional Hospital for supporting the project, with a special thanks to the involved research assistants, secretaries, nurses and physiotherapists, who\u2019s input and engagement made this study possible. In addition, we would like to extend our sincere gratitude to all the patients who generously participated and gave their time and effort during this study. Lastly, we would like to thank the funding parties, for providing the necessary financial support.

Publisher Copyright:
© The Author(s) 2024.

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