Human evolution: a tale from ancient genomes

Bastien Llamas, Eske Willerslev, Ludovic Antoine Alexandre Orlando

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    39 Citationer (Scopus)

    Abstract

    The field of human ancient DNA (aDNA) has moved from mitochondrial sequencing that suffered from contamination and provided limited biological insights, to become a fully genomic discipline that is changing our conception of human history. Recent successes include the sequencing of extinct hominins, and true population genomic studies of Bronze Age populations. Among the emerging areas of aDNA research, the analysis of past epigenomes is set to provide more new insights into human adaptation and disease susceptibility through time. Starting as a mere curiosity, ancient human genetics has become a major player in the understanding of our evolutionary history.This article is part of the themed issue 'Evo-devo in the genomics era, and the origins of morphological diversity'.

    OriginalsprogEngelsk
    Artikelnummer20150484
    TidsskriftRoyal Society of London. Philosophical Transactions B. Biological Sciences
    Vol/bind372
    Udgave nummer1713
    Antal sider11
    ISSN0962-8436
    DOI
    StatusUdgivet - 5 feb. 2017

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