Hyperbaric oxygen treatment may advance the outcome of antibiotic treatment of biofilm-related infections

Peter Østrup Jensen, Signe Agnete Møller, Simone Stjernekilde, Pernille Olsen, Claus Ernst Moser, Franziska Angelika Schwartz, Christian Johann Lerche, Niels Høiby, Ole Hyldegaard, Daniel Faurholt-Jepsen, Mette Kolpen

Publikation: Bidrag til bog/antologi/rapportBidrag til bog/antologiForskningpeer review

Abstract

Bacteria and fungi are able to aggregate together or on surfaces in densely packed microcolonies, facilitated by extracellular polymeric substances for cell protection and stability. These biofilms have proven to be extremely hard to eradicate and remove once established. In chronic infections, this condition can result in a high degree of morbidity and mortality as regular antibiotic treatments are ineffective against biofilms. In industrial facilities, the formation of biofilms can ruin production and result in enormous financial losses.In this book, the current state of antibiofilm research is presented by experts from around the world. Novel, cutting-edge techniques and new optimized strategies based on established methods are discussed in chapters focused on biofilm prevention, treatment and control for the application in clinical, industrial and veterinary settings.Antibiofilm strategies, such as chemical and enzymatic treatments, surface modification and coatings, quorum sensing inhibition and dispersal induction, phage therapy, cold plasma treatment, hyperbaric oxygen treatment, and metal-based nanomedicine are covered, among many others.This book contributes to the UNâ¤s Sustainable Development Goal 3: Good Health and Well-Being and is a valuable resource for healthcare professionals, microbiologists, academics and for educators to inform curricula of universities and colleges.
OriginalsprogEngelsk
TitelAntibiofilm Strategies - Hyperbaric oxygen treatment may advance the outcome of antibiotic treatment of biofilm-related infections
ForlagSpringer
Publikationsdato2022
Udgave9783031109911
Sider201-223
ISBN (Trykt)78-3-031-10994-2
ISBN (Elektronisk)978-3-031-10992-8
DOI
StatusUdgivet - 2022
NavnSpringer Series on Biofilms
Vol/bind11

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