Hypersensitivity to the diphtheria component in the Di-Te-Pol vaccine. A type I allergic reaction demonstrated by basophil histamine release

Per Stahl Skov; Inger Pelck; Finn Ebbesen; Lars Kærgaard Poulsen

doi:10.1111/j.1399-3038.1997.tb00171.x

Hypersensitivity to the diphtheria component in the Di-Te-Pol vaccine. A type I allergic reaction demonstrated by basophil histamine release

Per Stahl Skov^*, Inger Pelck, Finn Ebbesen, Lars Kærgaard Poulsen

^*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

31 Citationer (Scopus)

Abstract

We describe a two year-old multiallergic boy who developed generalized urticaria after the third Di-Te-Pol vaccination. A Type I reaction to the vaccine was demonstrated by performing basophil histamine release to the complete vaccine. Further, we found that the reaction could be exclusively ascribed to Diphtheria-Toxoid whereas no release was observed by the Polio and Tetanus component. The latter result was confirmed since no specific IgE to Tetanus Toxoid could be demonstrated.

Originalsprog	Engelsk
Tidsskrift	Pediatric Allergy and Immunology
Vol/bind	8
Udgave nummer	3
Sider (fra-til)	156-158
Antal sider	3
ISSN	0905-6157
DOI	https://doi.org/10.1111/j.1399-3038.1997.tb00171.x
Status	Udgivet - aug. 1997

Adgang til dokumentet

10.1111/j.1399-3038.1997.tb00171.x

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Citationsformater

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title = "Hypersensitivity to the diphtheria component in the Di-Te-Pol vaccine. A type I allergic reaction demonstrated by basophil histamine release",

abstract = "We describe a two year-old multiallergic boy who developed generalized urticaria after the third Di-Te-Pol vaccination. A Type I reaction to the vaccine was demonstrated by performing basophil histamine release to the complete vaccine. Further, we found that the reaction could be exclusively ascribed to Diphtheria-Toxoid whereas no release was observed by the Polio and Tetanus component. The latter result was confirmed since no specific IgE to Tetanus Toxoid could be demonstrated.",

keywords = "Allergy, Diphtheria, Histamine release, Hypersensitivity, Polio, Tetanus, Vaccine",

author = "Skov, {Per Stahl} and Inger Pelck and Finn Ebbesen and Poulsen, {Lars K{\ae}rgaard}",

year = "1997",

month = aug,

doi = "10.1111/j.1399-3038.1997.tb00171.x",

language = "English",

volume = "8",

pages = "156--158",

journal = "Pediatric Allergy and Immunology",

issn = "0905-6157",

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TY - JOUR

T1 - Hypersensitivity to the diphtheria component in the Di-Te-Pol vaccine. A type I allergic reaction demonstrated by basophil histamine release

AU - Skov, Per Stahl

AU - Pelck, Inger

AU - Ebbesen, Finn

AU - Poulsen, Lars Kærgaard

PY - 1997/8

Y1 - 1997/8

N2 - We describe a two year-old multiallergic boy who developed generalized urticaria after the third Di-Te-Pol vaccination. A Type I reaction to the vaccine was demonstrated by performing basophil histamine release to the complete vaccine. Further, we found that the reaction could be exclusively ascribed to Diphtheria-Toxoid whereas no release was observed by the Polio and Tetanus component. The latter result was confirmed since no specific IgE to Tetanus Toxoid could be demonstrated.

AB - We describe a two year-old multiallergic boy who developed generalized urticaria after the third Di-Te-Pol vaccination. A Type I reaction to the vaccine was demonstrated by performing basophil histamine release to the complete vaccine. Further, we found that the reaction could be exclusively ascribed to Diphtheria-Toxoid whereas no release was observed by the Polio and Tetanus component. The latter result was confirmed since no specific IgE to Tetanus Toxoid could be demonstrated.

KW - Allergy

KW - Diphtheria

KW - Histamine release

KW - Hypersensitivity

KW - Polio

KW - Tetanus

KW - Vaccine

UR - http://www.scopus.com/inward/record.url?scp=0031431526&partnerID=8YFLogxK

U2 - 10.1111/j.1399-3038.1997.tb00171.x

DO - 10.1111/j.1399-3038.1997.tb00171.x

M3 - Journal article

C2 - 9532258

AN - SCOPUS:0031431526

SN - 0905-6157

VL - 8

SP - 156

EP - 158

JO - Pediatric Allergy and Immunology

JF - Pediatric Allergy and Immunology

IS - 3

ER -