TY - JOUR
T1 - Caenorhabditis elegans as a model to determine fitness of antibiotic-resistant Salmonella enterica serovar typhimurium
AU - Paulander, Wilhelm Erik Axel
AU - Pennhag, Alexandra
AU - Andersson, Dan I.
AU - Maisnier-Patin, Sophie
PY - 2007
Y1 - 2007
N2 - We used the ability of Salmonella enterica serovar Typhimurium to colonize the gut of Caenorhabditis elegans to measure the fitness costs imposed by antibiotic resistance mutations. The fitness costs determined in the nematode were similar to those measured in mice, validating its use as a simple host model to evaluate bacterial fitness.
AB - We used the ability of Salmonella enterica serovar Typhimurium to colonize the gut of Caenorhabditis elegans to measure the fitness costs imposed by antibiotic resistance mutations. The fitness costs determined in the nematode were similar to those measured in mice, validating its use as a simple host model to evaluate bacterial fitness.
U2 - 10.1128/AAC.00615-06
DO - 10.1128/AAC.00615-06
M3 - Journal article
SN - 0066-4804
VL - 51
SP - 766
EP - 769
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 2
ER -