Abstract
Lean meat percentage is a critical production trait in pig breeding systems with direct implications for the sustainability of the industry. In this study, we conducted a genome-wide association study for lean meat percentage using a cohort of 850 Duroc × (Landrace × Yorkshire) crossbred pigs and we identified QTL on SSC3 and SSC18. Based on the predicted effect of imputed variants and using the PigGTEx database of molecular QTL, we prioritized candidate genes and SNPs located within the QTL regions, which may be involved in the regulation of porcine leanness. Our results indicate that a nonsense mutation in ZC3HAV1L on SSC18 has a direct effect on lean meat percentage.
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Animal Genetics |
| Vol/bind | 55 |
| Udgave nummer | 4 |
| Sider (fra-til) | 658-663 |
| ISSN | 0268-9146 |
| DOI | |
| Status | Udgivet - 2024 |
Bibliografisk note
Funding Information:This research was funded by the Danish Veterinary and Food Administration as part of the agreement of commissioned work between the Ministry of Food and Agriculture and Fisheries of Denmark and the University of Copenhagen and Statens Serum Institute, and by the Svineafgiftsfonden granted to SEGES Danish Pig Research Center. Tina N. Mahler and Minna Jakobsen are acknowledged for their great contributions to the laboratorial work.
Publisher Copyright:
© 2024 The Authors. Animal Genetics published by John Wiley & Sons Ltd on behalf of Stichting International Foundation for Animal Genetics.