Importance of chronic obstructive pulmonary disease for prognosis and diagnosis of congestive heart failure in patients with acute myocardial infarction

Erik Kjøller; Lars Køber; Kasper Iversen; Christian Torp-Pedersen; Trace Study Group

doi:10.1016/j.ejheart.2003.09.008

Importance of chronic obstructive pulmonary disease for prognosis and diagnosis of congestive heart failure in patients with acute myocardial infarction

Erik Kjøller, Lars Køber, Kasper Iversen, Christian Torp-Pedersen, Trace Study Group

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

45 Citationer (Scopus)

Abstract

Udgivelsesdato: 2004-Jan

Originalsprog	Engelsk
Tidsskrift	European Journal of Heart Failure
Vol/bind	6
Udgave nummer	1
Sider (fra-til)	71-7
Antal sider	6
ISSN	1388-9842
DOI	https://doi.org/10.1016/j.ejheart.2003.09.008
Status	Udgivet - 2004

Bibliografisk note

Keywords: Aged; Aged, 80 and over; Diagnosis, Differential; Female; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Prognosis; Pulmonary Disease, Chronic Obstructive; Risk Factors; Survival Rate

Adgang til dokumentet

10.1016/j.ejheart.2003.09.008

Citationsformater

@article{2a62e770118d11df803f000ea68e967b,

title = "Importance of chronic obstructive pulmonary disease for prognosis and diagnosis of congestive heart failure in patients with acute myocardial infarction",

abstract = "AIMS: To evaluate the importance of chronic obstructive pulmonary disease for prognosis and diagnosis of congestive heart failure in patients with acute myocardial infarction. METHOD AND RESULTS: Prospective registration of 6669 consecutive patients admitted with infarction and screened for a randomised controlled trial. A history of COPD was present in 765 (11.5%) patients. Thirty-day and 5-year survival in patients with chronic obstructive pulmonary disease was 86.3 and 42.9%. In patients without pulmonary disease the figures were 87.7 and 57.5%, respectively, giving a relative risk of 1.49 (1.35-1.65). In multivariate analysis the relative risk was 1.15 (1.04-1.28). The prevalence of congestive heart failure was 65.9% in patients with chronic obstructive pulmonary disease and 52.0% in patients without. This difference was most distinct in patients with normal or only slightly decreased left ventricular systolic function. In patients without congestive heart failure, chronic obstructive pulmonary disease was of prognostic importance [RR=1.44 (1.17-1.78)], but not in patients with congestive heart failure [RR=1.09 (0.96-1.23)]. CONCLUSION: Chronic obstructive pulmonary disease is a predictor of long-term mortality in patients with acute myocardial infarction without congestive heart failure, but is also a confounding factor for the diagnosis of congestive heart failure.",

author = "Erik Kj{\o}ller and Lars K{\o}ber and Kasper Iversen and Christian Torp-Pedersen and {Trace Study Group}",

note = "Keywords: Aged; Aged, 80 and over; Diagnosis, Differential; Female; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Prognosis; Pulmonary Disease, Chronic Obstructive; Risk Factors; Survival Rate",

year = "2004",

doi = "10.1016/j.ejheart.2003.09.008",

language = "English",

volume = "6",

pages = "71--7",

journal = "European Journal of Heart Failure",

issn = "1388-9842",

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TY - JOUR

T1 - Importance of chronic obstructive pulmonary disease for prognosis and diagnosis of congestive heart failure in patients with acute myocardial infarction

AU - Kjøller, Erik

AU - Køber, Lars

AU - Iversen, Kasper

AU - Torp-Pedersen, Christian

AU - Trace Study Group

N1 - Keywords: Aged; Aged, 80 and over; Diagnosis, Differential; Female; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Prognosis; Pulmonary Disease, Chronic Obstructive; Risk Factors; Survival Rate

PY - 2004

Y1 - 2004

N2 - AIMS: To evaluate the importance of chronic obstructive pulmonary disease for prognosis and diagnosis of congestive heart failure in patients with acute myocardial infarction. METHOD AND RESULTS: Prospective registration of 6669 consecutive patients admitted with infarction and screened for a randomised controlled trial. A history of COPD was present in 765 (11.5%) patients. Thirty-day and 5-year survival in patients with chronic obstructive pulmonary disease was 86.3 and 42.9%. In patients without pulmonary disease the figures were 87.7 and 57.5%, respectively, giving a relative risk of 1.49 (1.35-1.65). In multivariate analysis the relative risk was 1.15 (1.04-1.28). The prevalence of congestive heart failure was 65.9% in patients with chronic obstructive pulmonary disease and 52.0% in patients without. This difference was most distinct in patients with normal or only slightly decreased left ventricular systolic function. In patients without congestive heart failure, chronic obstructive pulmonary disease was of prognostic importance [RR=1.44 (1.17-1.78)], but not in patients with congestive heart failure [RR=1.09 (0.96-1.23)]. CONCLUSION: Chronic obstructive pulmonary disease is a predictor of long-term mortality in patients with acute myocardial infarction without congestive heart failure, but is also a confounding factor for the diagnosis of congestive heart failure.

AB - AIMS: To evaluate the importance of chronic obstructive pulmonary disease for prognosis and diagnosis of congestive heart failure in patients with acute myocardial infarction. METHOD AND RESULTS: Prospective registration of 6669 consecutive patients admitted with infarction and screened for a randomised controlled trial. A history of COPD was present in 765 (11.5%) patients. Thirty-day and 5-year survival in patients with chronic obstructive pulmonary disease was 86.3 and 42.9%. In patients without pulmonary disease the figures were 87.7 and 57.5%, respectively, giving a relative risk of 1.49 (1.35-1.65). In multivariate analysis the relative risk was 1.15 (1.04-1.28). The prevalence of congestive heart failure was 65.9% in patients with chronic obstructive pulmonary disease and 52.0% in patients without. This difference was most distinct in patients with normal or only slightly decreased left ventricular systolic function. In patients without congestive heart failure, chronic obstructive pulmonary disease was of prognostic importance [RR=1.44 (1.17-1.78)], but not in patients with congestive heart failure [RR=1.09 (0.96-1.23)]. CONCLUSION: Chronic obstructive pulmonary disease is a predictor of long-term mortality in patients with acute myocardial infarction without congestive heart failure, but is also a confounding factor for the diagnosis of congestive heart failure.

U2 - 10.1016/j.ejheart.2003.09.008

DO - 10.1016/j.ejheart.2003.09.008

M3 - Journal article

C2 - 15012921

SN - 1388-9842

VL - 6

SP - 71

EP - 77

JO - European Journal of Heart Failure

JF - European Journal of Heart Failure

IS - 1

ER -