Improved survival for multiple myeloma in denmark based on autologous stem cell transplantation and novel drug therapy in collaborative trials: analysis of accrual, prognostic variables, selection bias, and clinical behavior on survival in more than 1200 patients in trials of the nordic myeloma study group

Hans Erik Johnsen; Tobias W Klausen; Martin Boegsted; Stig Lenhoff; Peter Gimsing; Ilse Christiansen; Tobias Gedde-Dahl; Roald Lindås; Ulf-Henrik Mellqvist; Nordic Myeloma Study Group

doi:10.3816/CLML.2010.n.060

Improved survival for multiple myeloma in denmark based on autologous stem cell transplantation and novel drug therapy in collaborative trials: analysis of accrual, prognostic variables, selection bias, and clinical behavior on survival in more than 1200 patients in trials of the nordic myeloma study group

Hans Erik Johnsen, Tobias W Klausen, Martin Boegsted, Stig Lenhoff, Peter Gimsing, Ilse Christiansen, Tobias Gedde-Dahl, Roald Lindås, Ulf-Henrik Mellqvist, Nordic Myeloma Study Group

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

3 Citationer (Scopus)

Abstract

An unexplained survival difference was observed in the Nordic Myeloma Study Group (NMSG) high-dose therapy trial 5/94 in Denmark compared with Sweden and Norway; however, this difference was eliminated in the subsequent NMSG trial 7/98. It was hypothesized that a detailed analysis of potential explanations would reveal important information for future designs of clinical trials for multiple myeloma (MM) patients in Denmark.

Originalsprog	Engelsk
Tidsskrift	Clinical Lymphoma, Myeloma & Leukemia
Vol/bind	10
Udgave nummer	4
Sider (fra-til)	290-6
Antal sider	7
ISSN	2152-2650
DOI	https://doi.org/10.3816/CLML.2010.n.060
Status	Udgivet - 1 aug. 2010

Adgang til dokumentet

10.3816/CLML.2010.n.060

Citationsformater

Johnsen, H. E., Klausen, T. W., Boegsted, M., Lenhoff, S., Gimsing, P., Christiansen, I., Gedde-Dahl, T., Lindås, R., Mellqvist, U.-H., & Nordic Myeloma Study Group (2010). Improved survival for multiple myeloma in denmark based on autologous stem cell transplantation and novel drug therapy in collaborative trials: analysis of accrual, prognostic variables, selection bias, and clinical behavior on survival in more than 1200 patients in trials of the nordic myeloma study group. Clinical Lymphoma, Myeloma & Leukemia, 10(4), 290-6. https://doi.org/10.3816/CLML.2010.n.060

Improved survival for multiple myeloma in denmark based on autologous stem cell transplantation and novel drug therapy in collaborative trials: analysis of accrual, prognostic variables, selection bias, and clinical behavior on survival in more than 1200 patients in trials of the nordic myeloma study group. / Johnsen, Hans Erik; Klausen, Tobias W; Boegsted, Martin et al.
I: Clinical Lymphoma, Myeloma & Leukemia, Bind 10, Nr. 4, 01.08.2010, s. 290-6.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Johnsen, HE, Klausen, TW, Boegsted, M, Lenhoff, S, Gimsing, P, Christiansen, I, Gedde-Dahl, T, Lindås, R, Mellqvist, U-H & Nordic Myeloma Study Group 2010, 'Improved survival for multiple myeloma in denmark based on autologous stem cell transplantation and novel drug therapy in collaborative trials: analysis of accrual, prognostic variables, selection bias, and clinical behavior on survival in more than 1200 patients in trials of the nordic myeloma study group', Clinical Lymphoma, Myeloma & Leukemia, bind 10, nr. 4, s. 290-6. https://doi.org/10.3816/CLML.2010.n.060

Johnsen HE, Klausen TW, Boegsted M, Lenhoff S, Gimsing P, Christiansen I et al. Improved survival for multiple myeloma in denmark based on autologous stem cell transplantation and novel drug therapy in collaborative trials: analysis of accrual, prognostic variables, selection bias, and clinical behavior on survival in more than 1200 patients in trials of the nordic myeloma study group. Clinical Lymphoma, Myeloma & Leukemia. 2010 aug. 1;10(4):290-6. doi: 10.3816/CLML.2010.n.060

Johnsen, Hans Erik ; Klausen, Tobias W ; Boegsted, Martin et al. / Improved survival for multiple myeloma in denmark based on autologous stem cell transplantation and novel drug therapy in collaborative trials: analysis of accrual, prognostic variables, selection bias, and clinical behavior on survival in more than 1200 patients in trials of the nordic myeloma study group. I: Clinical Lymphoma, Myeloma & Leukemia. 2010 ; Bind 10, Nr. 4. s. 290-6.

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abstract = "An unexplained survival difference was observed in the Nordic Myeloma Study Group (NMSG) high-dose therapy trial 5/94 in Denmark compared with Sweden and Norway; however, this difference was eliminated in the subsequent NMSG trial 7/98. It was hypothesized that a detailed analysis of potential explanations would reveal important information for future designs of clinical trials for multiple myeloma (MM) patients in Denmark.",

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AU - Johnsen, Hans Erik

AU - Klausen, Tobias W

AU - Boegsted, Martin

AU - Lenhoff, Stig

AU - Gimsing, Peter

AU - Christiansen, Ilse

AU - Gedde-Dahl, Tobias

AU - Lindås, Roald

AU - Mellqvist, Ulf-Henrik

AU - Nordic Myeloma Study Group

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AB - An unexplained survival difference was observed in the Nordic Myeloma Study Group (NMSG) high-dose therapy trial 5/94 in Denmark compared with Sweden and Norway; however, this difference was eliminated in the subsequent NMSG trial 7/98. It was hypothesized that a detailed analysis of potential explanations would reveal important information for future designs of clinical trials for multiple myeloma (MM) patients in Denmark.

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DO - 10.3816/CLML.2010.n.060

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