In vivo imaging of cerebral serotonin transporter and serotonin(2A) receptor binding in 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") and hallucinogen users

David Erritzoe, Vibe Frøkjær, Klaus K Holst, Maria Christoffersen, Sys Stybe Johansen, Claus Svarer, Jacob Madsen, Peter M Rasmussen, Thomas Ramsøy, Terry L Jernigan, Gitte M Knudsen

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73 Citationer (Scopus)

Abstract

Both hallucinogens and 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") have direct agonistic effects on postsynaptic serotonin(2A) receptors, the key site for hallucinogenic actions. In addition, MDMA is a potent releaser and reuptake inhibitor of presynaptic serotonin.
OriginalsprogEngelsk
TidsskriftArchives of General Psychiatry
Vol/bind68
Udgave nummer6
Sider (fra-til)562-76
Antal sider15
ISSN0003-990X
DOI
StatusUdgivet - 2011

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