Increasing genetic variance of body mass index during the Swedish obesity epidemic

Benjamin Rokholm; Karri Silventoinen; Per Tynelius; Michael Gamborg; Thorkild I A Sørensen; Finn Rasmussen

doi:10.1371/journal.pone.0027135

Increasing genetic variance of body mass index during the Swedish obesity epidemic

Benjamin Rokholm, Karri Silventoinen, Per Tynelius, Michael Gamborg, Thorkild I A Sørensen, Finn Rasmussen

Institut for Folkesundhedsvidenskab

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

63 Citationer (Scopus)

Abstract

There is no doubt that the dramatic worldwide increase in obesity prevalence is due to changes in environmental factors. However, twin and family studies suggest that genetic differences are responsible for the major part of the variation in adiposity within populations. Recent studies show that the genetic effects on body mass index (BMI) may be stronger when combined with presumed risk factors for obesity. We tested the hypothesis that the genetic variance of BMI has increased during the obesity epidemic.

Originalsprog	Engelsk
Tidsskrift	P L o S One
Vol/bind	6
Udgave nummer	11
Sider (fra-til)	e27135
ISSN	1932-6203
DOI	https://doi.org/10.1371/journal.pone.0027135 https://doi.org/10.1371/journal.pone.0027135
Status	Udgivet - 2011

Adgang til dokumentet

Citationsformater

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AU - Gamborg, Michael

AU - Sørensen, Thorkild I A

AU - Rasmussen, Finn

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