Insights into mitotic checkpoint by integrating CRISPR and RNAi

Gang Zhang

doi:10.1080/23723556.2019.1603436

Insights into mitotic checkpoint by integrating CRISPR and RNAi

Gang Zhang

Protein Signaling Program

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

1 Citationer (Scopus)

Abstract

Our recent study of the mitotic checkpoint protein BUB1 (budding uninhibited by benzimidazoles 1) revealed several apparent BUB1 knock-out cell lines expressing low levels of BUB1 protein sufficient to support spindle assembly checkpoint activity. This rings alarm bells on the application of CRISPR technology.

Originalsprog	Engelsk
Artikelnummer	1603436
Tidsskrift	Molecular & Cellular Oncology
Vol/bind	6
Udgave nummer	4
ISSN	2372-3556
DOI	https://doi.org/10.1080/23723556.2019.1603436
Status	Udgivet - 2019

Adgang til dokumentet

10.1080/23723556.2019.1603436

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548497/pdf/kmco-06-04-1603436.pdfLicens: Andet

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Citationsformater

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title = "Insights into mitotic checkpoint by integrating CRISPR and RNAi",

abstract = "Our recent study of the mitotic checkpoint protein BUB1 (budding uninhibited by benzimidazoles 1) revealed several apparent BUB1 knock-out cell lines expressing low levels of BUB1 protein sufficient to support spindle assembly checkpoint activity. This rings alarm bells on the application of CRISPR technology.",

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AB - Our recent study of the mitotic checkpoint protein BUB1 (budding uninhibited by benzimidazoles 1) revealed several apparent BUB1 knock-out cell lines expressing low levels of BUB1 protein sufficient to support spindle assembly checkpoint activity. This rings alarm bells on the application of CRISPR technology.

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DO - 10.1080/23723556.2019.1603436

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