Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers

Darren Plant, Edward Flynn, Hamdi Mbarek, Philippe Dieudé, François Cornelis, Lisbeth Arlestig, Solbritt Rantapää Dahlqvist, George Goulielmos, Dimitrios T Boumpas, Prodromos Sidiropoulos, Julia S Johansen, Lykke M Ørnbjerg, Merete Lund Hetland, Lars Klareskog, Andrew Filer, Christopher D Buckley, Karim Raza, Torsten Witte, Reinhold E Schmidt, Jane Worthington

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76 Citationer (Scopus)

Abstract

Genetic factors have a substantial role in determining development of rheumatoid arthritis (RA), and are likely to account for 50-60% of disease susceptibility. Genome-wide association studies have identified non-human leucocyte antigen RA susceptibility loci which associate with RA with low-to-moderate risk.
OriginalsprogEngelsk
TidsskriftAnnals of the Rheumatic Diseases
Vol/bind69
Udgave nummer8
Sider (fra-til)1548-53
Antal sider6
ISSN0003-4967
DOI
StatusUdgivet - 1 aug. 2010

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