Ischemic CA-1 pyramidal cell loss is prevented by preischemic colchicine destruction of dentate gyrus granule cells.

Flemming Fryd Johansen; M B Jørgensen; N H Diemer

Ischemic CA-1 pyramidal cell loss is prevented by preischemic colchicine destruction of dentate gyrus granule cells.

Flemming Fryd Johansen, M B Jørgensen, N H Diemer

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

106 Citationer (Scopus)

Abstract

Udgivelsesdato: 1986-Jul-9

Originalsprog	Engelsk
Tidsskrift	Brain Research
Vol/bind	377
Udgave nummer	2
Sider (fra-til)	344-7
Antal sider	3
ISSN	0006-8993
Status	Udgivet - 1986
Udgivet eksternt	Ja

Bibliografisk note

Keywords: Animals; Colchicine; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Ischemic Attack, Transient; Male; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptic Transmission

Citationsformater

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title = "Ischemic CA-1 pyramidal cell loss is prevented by preischemic colchicine destruction of dentate gyrus granule cells.",

abstract = "Hippocampal CA-1 pyramidal cell damage was produced by 20 min of cerebral ischemia. Colchicine destruction of the dentate gyrus granule cells 11 days before ischemia prevented the CA-1 cell loss. It is suggested that the protective effect of degranulation on ischemic CA-1 pyramidal cell damage is due to reduction of glutamate release in CA-1 during and after ischemia.",

author = "Johansen, {Flemming Fryd} and J{\o}rgensen, {M B} and Diemer, {N H}",

note = "Keywords: Animals; Colchicine; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Ischemic Attack, Transient; Male; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptic Transmission",

year = "1986",

language = "English",

volume = "377",

pages = "344--7",

journal = "Brain Research",

issn = "0006-8993",

publisher = "Elsevier",

number = "2",

}

TY - JOUR

T1 - Ischemic CA-1 pyramidal cell loss is prevented by preischemic colchicine destruction of dentate gyrus granule cells.

AU - Johansen, Flemming Fryd

AU - Jørgensen, M B

AU - Diemer, N H

N1 - Keywords: Animals; Colchicine; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Ischemic Attack, Transient; Male; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptic Transmission

PY - 1986

Y1 - 1986

N2 - Hippocampal CA-1 pyramidal cell damage was produced by 20 min of cerebral ischemia. Colchicine destruction of the dentate gyrus granule cells 11 days before ischemia prevented the CA-1 cell loss. It is suggested that the protective effect of degranulation on ischemic CA-1 pyramidal cell damage is due to reduction of glutamate release in CA-1 during and after ischemia.

AB - Hippocampal CA-1 pyramidal cell damage was produced by 20 min of cerebral ischemia. Colchicine destruction of the dentate gyrus granule cells 11 days before ischemia prevented the CA-1 cell loss. It is suggested that the protective effect of degranulation on ischemic CA-1 pyramidal cell damage is due to reduction of glutamate release in CA-1 during and after ischemia.

M3 - Journal article

C2 - 2873869

SN - 0006-8993

VL - 377

SP - 344

EP - 347

JO - Brain Research

JF - Brain Research

IS - 2

ER -