Schinus terebinthifolia Raddi—Untargeted Metabolomics Approach to Investigate the Chemical Variation in Volatile and Non-Volatile Compounds

Mara Junqueira Carneiro, Guilherme Perez Pinheiro, Elisa Ribeiro Miranda Antunes, Leandro Wang Hantao, Thomas Moritz, Alexandra Christine Helena Frankland Sawaya*

*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

7 Downloads (Pure)

Abstract

Context: Schinus terebinthifolia Raddi is used in Brazilian folk medicine due to the wound healing and antiseptic properties of its bark, and its fruit are used as a condiment. However, the aerial parts of this plant have been studied and present some bioactive compounds as well. Objectives: The aim of this study was to investigate the variation in volatile and non-volatile composition of S. terebinthifolia leaves using untargeted metabolomics. Material and Methods: The leaves of four trees were collected over one year; ethanolic extracts were analyzed by UHPLC-MS and fresh leaves were analyzed by GC-MS using HS-SPME. The data were processed using online software. Results: The results suggest seasonality interfered little with the chemical composition of leaves. On the other hand, the sex of the plant clearly determined the chemical composition of both volatile and non-volatile compounds. Discussion and conclusions: Chemical variability between plants with male and female flowers is fundamental information for the standardized use of its leaves. Compounds with important biological activities were putatively identified, confirming the potential use of S. terebinthifolia leaves as a source of bioactive compounds, reducing waste and increasing economic gains for local farmers throughout the year.

OriginalsprogEngelsk
Artikelnummer612
TidsskriftMetabolites
Vol/bind14
Udgave nummer11
Antal sider14
ISSN2218-1989
DOI
StatusUdgivet - 2024

Bibliografisk note

Funding Information:
We thank Institute of Biology of State University of Campinas, S\u00E3o Paulo Research Foundation (FAPESP), Funda\u00E7\u00E3o Coordena\u00E7\u00E3o de Aperfei\u00E7oamento de Pessoal de N\u00EDvel Superior (CAPES), and The National Council for Scientific and Technological Development (CNPq) for financial support.

Funding Information:
Research was supported mainly by S\u00E3o Paulo Research Foundation (FAPESP) (2016/11524-9; 2018/11069; 2018/11726-6) and, in part, by the Coordena\u00E7\u00E3o de Aperfei\u00E7oamento de Pessoal de N\u00EDvel Superior\u2014Brasil (CAPES)\u2014Finance Codes 001 and 88887.973568/2024-00. The National Council for Scientific and Technological Development (CNPq) (306100/2021-5), Knut and Alice Wallenberg Foundation (KAW2018.0094), Novo Nordisk Foundation (NNF18CC0034900, NNF23SA0084103).

Publisher Copyright:
© 2024 by the authors.

Citationsformater