@article{93ac23a078c711dd81b0000ea68e967b,
title = "Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria",
abstract = "Gender-specific and parity-dependent acquired antibody recognition is characteristic of variant surface antigens (VSA) expressed by chondroitin sulfate A (CSA)-adherent Plasmodium falciparum involved in pregnancy-associated malaria (PAM). However, antibody recognition of recombinant products of a specific VSA gene (2O2var1) implicated in PAM and transcribed by a CSA-adhering parasite line did not have these characteristics. Furthermore, we could not demonstrate preferential transcription of 2O2var1 in the CSA-adhering line versus the unselected, parental isolate. Our data call for circumspection regarding the molecular identity of the parasite ligand mediating adhesion to CSA in PAM.",
author = "Jensen, {Anja T R} and Zornig, {Hanne D} and Caecilie Buhmann and Ali Salanti and Koram, {Kwadwo A} and Riley, {Eleanor M} and Theander, {Thor G} and Lars Hviid and Trine Staalsoe",
note = "Keywords: Animals; Antibodies, Protozoan; Chondroitin Sulfates; Female; Humans; Immunoglobulin G; Malaria, Falciparum; Male; Parity; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Protozoan Proteins; Sex Factors",
year = "2003",
doi = "10.1128/IAI.71.7.4193–4196.2003",
language = "English",
volume = "71",
pages = "4193--6",
journal = "Infection and Immunity",
issn = "0019-9567",
publisher = "American Society for Microbiology",
number = "7",
}