Low prevalence of retinopathy among Greenland Inuit

Trine Louise Jul Larsen; Marit Eika Jørgensen; Michael Lynge Pedersen; Henrik Lund-Andersen; Marianne Valerius; Ellen Juul; Stine Byberg

doi:10.1080/22423982.2021.1938420

Low prevalence of retinopathy among Greenland Inuit

Trine Louise Jul Larsen^*, Marit Eika Jørgensen, Michael Lynge Pedersen, Henrik Lund-Andersen, Marianne Valerius, Ellen Juul, Stine Byberg

^*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

10 Citationer (Scopus)

45 Downloads (Pure)

Abstract

To assess the prevalence of diabetic retinopathy (DR) among persons with diabetes and prediabetes participating in the 2018 Population Health Survey in Greenland (B2018), a follow-up survey of three previous health surveys. Participants were invited to a diabetes complication screening. We assessed the prevalence of DR using Optos Daytona Ultra-wide field fundus camera and assessed differences in prevalence according to demographic and clinical characteristics using chi square test and a t-test and assessed DR based on ethnicity. The overall prevalence of DR was 2% (10/483). Among participants with HbA₁c ≥48 mmol/mol (6.5%) DR prevalence was 9% (9/91), compared with <1% (1/382) among participants with HbA₁c <48 mmol/mol (6.5%). All participants with DR lived in towns. The mean Inuit genetic admixture was lower among participants with DR. The prevalence of DR is low in Greenland and almost non-existent among persons with HbA₁c below the diabetes threshold.

Originalsprog	Engelsk
Artikelnummer	1938420
Tidsskrift	International Journal of Circumpolar Health
Vol/bind	80
Udgave nummer	1
ISSN	1239-9736
DOI	https://doi.org/10.1080/22423982.2021.1938420
Status	Udgivet - 2021

Bibliografisk note

Funding Information:
This project was funded by the Novo Nordisk Foundation [NNF17OC0028136, NNF17SH002719]. The funding agency had no role in the study design or in the collection or interpretation of the data. We are grateful to OPTOS Scotland for the opportunity to borrow the Daytona OPTOS camera for the examinations conducted in the study.

Publisher Copyright:
© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

Adgang til dokumentet

10.1080/22423982.2021.1938420Licens: CC BY-NC

FulltextForlagets udgivne version, 1,27 MBLicens: CC BY-NC

Biblioteksadgang?

Tjek tilgængelighed hos det Kgl. Bibliotek

Citationsformater

@article{78c1c36b6058446b89f20744a2135abe,

title = "Low prevalence of retinopathy among Greenland Inuit",

abstract = "To assess the prevalence of diabetic retinopathy (DR) among persons with diabetes and prediabetes participating in the 2018 Population Health Survey in Greenland (B2018), a follow-up survey of three previous health surveys. Participants were invited to a diabetes complication screening. We assessed the prevalence of DR using Optos Daytona Ultra-wide field fundus camera and assessed differences in prevalence according to demographic and clinical characteristics using chi square test and a t-test and assessed DR based on ethnicity. The overall prevalence of DR was 2% (10/483). Among participants with HbA1c ≥48 mmol/mol (6.5%) DR prevalence was 9% (9/91), compared with <1% (1/382) among participants with HbA1c <48 mmol/mol (6.5%). All participants with DR lived in towns. The mean Inuit genetic admixture was lower among participants with DR. The prevalence of DR is low in Greenland and almost non-existent among persons with HbA1c below the diabetes threshold.",

keywords = "Diabetes, Greenland Inuit, Retinopathy",

author = "Larsen, {Trine Louise Jul} and J{\o}rgensen, {Marit Eika} and Pedersen, {Michael Lynge} and Henrik Lund-Andersen and Marianne Valerius and Ellen Juul and Stine Byberg",

note = "Publisher Copyright: {\textcopyright} 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.",

year = "2021",

doi = "10.1080/22423982.2021.1938420",

language = "English",

volume = "80",

journal = "International Journal of Circumpolar Health",

issn = "1239-9736",

publisher = "International Association of Circumpolar Health Publishers",

number = "1",

}

TY - JOUR

T1 - Low prevalence of retinopathy among Greenland Inuit

AU - Larsen, Trine Louise Jul

AU - Jørgensen, Marit Eika

AU - Pedersen, Michael Lynge

AU - Lund-Andersen, Henrik

AU - Valerius, Marianne

AU - Juul, Ellen

AU - Byberg, Stine

PY - 2021

Y1 - 2021

N2 - To assess the prevalence of diabetic retinopathy (DR) among persons with diabetes and prediabetes participating in the 2018 Population Health Survey in Greenland (B2018), a follow-up survey of three previous health surveys. Participants were invited to a diabetes complication screening. We assessed the prevalence of DR using Optos Daytona Ultra-wide field fundus camera and assessed differences in prevalence according to demographic and clinical characteristics using chi square test and a t-test and assessed DR based on ethnicity. The overall prevalence of DR was 2% (10/483). Among participants with HbA1c ≥48 mmol/mol (6.5%) DR prevalence was 9% (9/91), compared with <1% (1/382) among participants with HbA1c <48 mmol/mol (6.5%). All participants with DR lived in towns. The mean Inuit genetic admixture was lower among participants with DR. The prevalence of DR is low in Greenland and almost non-existent among persons with HbA1c below the diabetes threshold.

AB - To assess the prevalence of diabetic retinopathy (DR) among persons with diabetes and prediabetes participating in the 2018 Population Health Survey in Greenland (B2018), a follow-up survey of three previous health surveys. Participants were invited to a diabetes complication screening. We assessed the prevalence of DR using Optos Daytona Ultra-wide field fundus camera and assessed differences in prevalence according to demographic and clinical characteristics using chi square test and a t-test and assessed DR based on ethnicity. The overall prevalence of DR was 2% (10/483). Among participants with HbA1c ≥48 mmol/mol (6.5%) DR prevalence was 9% (9/91), compared with <1% (1/382) among participants with HbA1c <48 mmol/mol (6.5%). All participants with DR lived in towns. The mean Inuit genetic admixture was lower among participants with DR. The prevalence of DR is low in Greenland and almost non-existent among persons with HbA1c below the diabetes threshold.

KW - Diabetes

KW - Greenland Inuit

KW - Retinopathy

U2 - 10.1080/22423982.2021.1938420

DO - 10.1080/22423982.2021.1938420

M3 - Journal article

C2 - 34134608

AN - SCOPUS:85108316379

SN - 1239-9736

VL - 80

JO - International Journal of Circumpolar Health

JF - International Journal of Circumpolar Health

IS - 1

M1 - 1938420

ER -