Lumbar Modic Changes - A Comparison Between Findings at Low-and High-field MRI

Bidragets oversatte titel: Lumbale modic forandringer- en sammenligning mellem fund ved lav og høj felt MRI

Tom Bendix, Joan S Sorensen, Gustaf A C Henriksson, Jørn Espen Bolstad, Eva K Narvestad, Tue Secher Jensen

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    49 Citationer (Scopus)

    Abstract

    Study design
    A cross-sectional observational study.
    Objective
    To investigate if there is a difference in findings of lumbar Modic changes in low-field (0.3 Tesla) magnetic resonance imaging (MRI) as compared to high field (1.5 Tesla).
    Summary of background data
    It is a challenge to give patients with low back pain (LBP) a specific diagnosis. Modic changes as seen on MRI have been reported to be a possible source of pain. However, it is unclear if the diagnosis is independent on the field strength.
    Methods
    Twenty patients with Modic changes, 11 women and 9 men (mean age 53.6, range 29-81), with or without sciatica, seen in a Danish outpatient LBP clinic were included. All patients had MRI scans on both a high-field and a low-field MRI scanner. Two radiologists evaluated all lumbar endplates independently using a standardized evaluation protocol. Kappa statistics were used to analyze the inter-observer reproducibility. To analyze the difference between low- and high-field MRI we used paired t-test.
    Results
    The total number of Modic changes diagnosed with high-field MRI was significantly higher as compared to low-field MRI. However, 3-4 times as many Modic type 1 changes were found with low-field MRI as compared to high-field. Contrarily, with high-field MRI type 2 changes were diagnosed twice as often.
    Conclusion
    There was a significant difference between low- and high-field MRI regarding the overall prevalence of any Modic change, but this had opposite directions for type 1 and 2: Type 2 dominated in low field, and conversely in high field. The type of MRI unit should be taken into consideration when diagnosing patients with Modic changes.

    Bidragets oversatte titelLumbale modic forandringer- en sammenligning mellem fund ved lav og høj felt MRI
    OriginalsprogEngelsk
    TidsskriftSpine (Philadelphia, 1976)
    Vol/bind37
    Udgave nummer20
    Sider (fra-til)1756–1762
    ISSN0362-2436
    DOI
    StatusUdgivet - 2012

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