Management and survival of patients admitted with an exacerbation of COPD: comparison of two Danish patient cohorts

Nanna Eriksen; Jørgen Vestbo

doi:10.1111/j.1752-699X.2009.00177.x

Management and survival of patients admitted with an exacerbation of COPD: comparison of two Danish patient cohorts

Nanna Eriksen, Jørgen Vestbo

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

26 Citationer (Scopus)

Abstract

Udgivelsesdato: 2010-Oct

Originalsprog	Engelsk
Tidsskrift	Clinical Respiratory Journal
Vol/bind	4
Udgave nummer	4
Sider (fra-til)	208-14
Antal sider	6
ISSN	1752-6981
DOI	https://doi.org/10.1111/j.1752-699X.2009.00177.x
Status	Udgivet - 2010

Bibliografisk note

Adgang til dokumentet

10.1111/j.1752-699X.2009.00177.x

Citationsformater

@article{f776f6837a9e4599b983aff75fdd9a2b,

title = "Management and survival of patients admitted with an exacerbation of COPD: comparison of two Danish patient cohorts",

abstract = "INTRODUCTION: The aim of this study was to describe the management and prognosis related to a hospital admission for acute exacerbation of chronic obstructive pulmonary disease and to compare results to an earlier study. OBJECTIVES AND METHODS: This is a retrospective study of 300 consecutively discharged patients admitted in 2006-2007 with an exacerbation of chronic obstructive pulmonary disease from three respiratory departments. Data were collected from patient charts and compared with a replicate study done in 2001. RESULTS: The mean age was 72.1years; 61.7% were women. Mean forced expiratory volume in 1s was 37.6% of predicted. On admission, 11.3% were treated with non-invasive ventilation, and 84.3% were given systemic corticosteroids. In-hospital mortality was 4.7%. At discharge, treatment with inhaled corticosteroids or at least one long-acting bronchodilator was given to 86.7% and 89% of patients, respectively, which was significantly higher than for similarly sampled patients in 2001. Mortality in 30days and 1year after discharge was 4.5% and 25.5%, respectively, compared with 5.5% and 30.3% in 2001, the 12-month mortality being significantly lower (P=0.03). Readmission rate in the 12months following discharge was 42.3%. Long-term oxygen treatment, treatment with anti-dysrhythmic drugs and lack of outpatient follow-up were independent predictors of 1-year mortality. Risk of readmission was increased with dependence in self-care activities, previous admissions and treatment with strong analgesics. CONCLUSIONS: Over a period of 6years, a significantly higher number of patients are being treated according to guidelines. Survival following discharge increased over the same period.",

author = "Nanna Eriksen and J{\o}rgen Vestbo",

note = "{\textcopyright} 2009 Blackwell Publishing Ltd.",

year = "2010",

doi = "10.1111/j.1752-699X.2009.00177.x",

language = "English",

volume = "4",

pages = "208--14",

journal = "Clinical Respiratory Journal",

issn = "1752-6981",

publisher = "Wiley-Blackwell",

number = "4",

}

TY - JOUR

T1 - Management and survival of patients admitted with an exacerbation of COPD: comparison of two Danish patient cohorts

AU - Eriksen, Nanna

AU - Vestbo, Jørgen

PY - 2010

Y1 - 2010

N2 - INTRODUCTION: The aim of this study was to describe the management and prognosis related to a hospital admission for acute exacerbation of chronic obstructive pulmonary disease and to compare results to an earlier study. OBJECTIVES AND METHODS: This is a retrospective study of 300 consecutively discharged patients admitted in 2006-2007 with an exacerbation of chronic obstructive pulmonary disease from three respiratory departments. Data were collected from patient charts and compared with a replicate study done in 2001. RESULTS: The mean age was 72.1years; 61.7% were women. Mean forced expiratory volume in 1s was 37.6% of predicted. On admission, 11.3% were treated with non-invasive ventilation, and 84.3% were given systemic corticosteroids. In-hospital mortality was 4.7%. At discharge, treatment with inhaled corticosteroids or at least one long-acting bronchodilator was given to 86.7% and 89% of patients, respectively, which was significantly higher than for similarly sampled patients in 2001. Mortality in 30days and 1year after discharge was 4.5% and 25.5%, respectively, compared with 5.5% and 30.3% in 2001, the 12-month mortality being significantly lower (P=0.03). Readmission rate in the 12months following discharge was 42.3%. Long-term oxygen treatment, treatment with anti-dysrhythmic drugs and lack of outpatient follow-up were independent predictors of 1-year mortality. Risk of readmission was increased with dependence in self-care activities, previous admissions and treatment with strong analgesics. CONCLUSIONS: Over a period of 6years, a significantly higher number of patients are being treated according to guidelines. Survival following discharge increased over the same period.

AB - INTRODUCTION: The aim of this study was to describe the management and prognosis related to a hospital admission for acute exacerbation of chronic obstructive pulmonary disease and to compare results to an earlier study. OBJECTIVES AND METHODS: This is a retrospective study of 300 consecutively discharged patients admitted in 2006-2007 with an exacerbation of chronic obstructive pulmonary disease from three respiratory departments. Data were collected from patient charts and compared with a replicate study done in 2001. RESULTS: The mean age was 72.1years; 61.7% were women. Mean forced expiratory volume in 1s was 37.6% of predicted. On admission, 11.3% were treated with non-invasive ventilation, and 84.3% were given systemic corticosteroids. In-hospital mortality was 4.7%. At discharge, treatment with inhaled corticosteroids or at least one long-acting bronchodilator was given to 86.7% and 89% of patients, respectively, which was significantly higher than for similarly sampled patients in 2001. Mortality in 30days and 1year after discharge was 4.5% and 25.5%, respectively, compared with 5.5% and 30.3% in 2001, the 12-month mortality being significantly lower (P=0.03). Readmission rate in the 12months following discharge was 42.3%. Long-term oxygen treatment, treatment with anti-dysrhythmic drugs and lack of outpatient follow-up were independent predictors of 1-year mortality. Risk of readmission was increased with dependence in self-care activities, previous admissions and treatment with strong analgesics. CONCLUSIONS: Over a period of 6years, a significantly higher number of patients are being treated according to guidelines. Survival following discharge increased over the same period.

U2 - 10.1111/j.1752-699X.2009.00177.x

DO - 10.1111/j.1752-699X.2009.00177.x

M3 - Journal article

SN - 1752-6981

VL - 4

SP - 208

EP - 214

JO - Clinical Respiratory Journal

JF - Clinical Respiratory Journal

IS - 4

ER -